An interchangeable prion-like domain is required for Ty1 retrotransposition.

Unlabelled: Retrotransposons and retroviruses shape genome evolution and can negatively impact genome function. and its close relatives harbor several families of LTR-retrotransposons, the most abundant being Ty1 in several laboratory strains. The cytosolic foci that nucleate Ty1 virus-like particle (VLP) assembly are not well-understood.