Publications by authors named "Ricarda Riepl"
Article Synopsis
- The study examines rare but significant complications associated with cochlear implantation, specifically focusing on subcutaneous emphysema in three patients.
- Emphysema developed in these patients several months post-surgery, likely triggered by habits like nose blowing and CPAP therapy, with literature noting similar cases linked to Eustachian tube dysfunction and nasal issues.
- Treatment typically involves conservative measures such as pressure bandaging, while surgical intervention is reserved for severe instances, underscoring the importance of preventive measures for at-risk patients.
Article Synopsis
- Complex surgeries often involve using autologous cartilage from places like the rib to reconstruct lesions in aural, nasal, and tracheal cartilage, but cartilage tissue engineering (CTE) offers a potential alternative.
- Researchers utilized a custom glass bioreactor to improve cell migration into decellularized porcine cartilage scaffolds seeded with human nasal chondrocytes, finding that this dynamic culture significantly enhances cell migration compared to static methods.
- While the bioreactor initially improved cell differentiation in the first 14 days, maintaining this differentiation over time remains a key challenge for advancing clinical applications in cartilage regeneration.
Background: Over the last decades conventional cochlear implant (CI) surgery has remained essentially unchanged. Nevertheless, alternative implantation techniques to further improve patient outcomes such as endaural implantation or robot-assisted surgery have been proposed in recent years. However, none of these have gained acceptance in clinical routine, thus confirming a demand for new developments.
View Article and Find Full Text PDFAutologous cartilage as donor tissue for various surgical reconstructions such as nasal septum regeneration is limited and associated with donor site morbidity. Our goal was to evaluate a new resorbable chondroconductive biomaterial made of decellularized porcine nasal septum cartilage compared with autologous native auricular cartilage as the gold standard. In order to examine the material and determine its long-term outcome further, we used subcutaneous implantation and septal implantation in an orthotopic rabbit model.
View Article and Find Full Text PDFThe implantation of autologous cartilage as the gold standard operative procedure for the reconstruction of cartilage defects in the head and neck region unfortunately implicates a variety of negative effects at the donor site. Tissue-engineered cartilage appears to be a promising alternative. However, due to the complex requirements, the optimal material is yet to be determined.
View Article and Find Full Text PDF[Castleman's Disease - A Case Series of a Rare Lymphoproliferative Disease].
Laryngorhinootologie
August 2017
Castleman's disease is a very rare and potentially severe lymphoproliferative disorder. First sign may be cervical lymphadenitis, requiring sufficient support in diagnosis and therapy by an ENT specialist. Based on a case series the current manuscript gives an overview of the symptoms, the course of disease and the therapy options.
View Article and Find Full Text PDFObjectives/hypothesis: Septal deviation and hypertrophic inferior turbinates are a frequent cause of nasal breathing disorders. The goal of this study was to prove the effectiveness and safety of three current turbinoplasty techniques.
Study Design: This is a prospective, three-arm, single-blinded, single-center, randomized controlled trial.