Publications by authors named "Ricarda Garcia-Sanchez"

Asymptomatic IgM gammopathy encompasses IgM monoclonal gammopathy of undetermined significance (MGUS) and asymptomatic Waldenström macroglobulinemia (AWM), both having a risk of progression to symptomatic disease. Here, we assessed the risk of progression and the mortality of 956 patients with asymptomatic IgM gammopathy across 25 Spanish centers. After a median follow-up of 5.

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Objectives: To describe the incorporation of monoclonal antibodies (mAb) in real-world (RW) practice for the treatment of patients with relapsed refractory multiple myeloma (RRMM) in a setting with other treatment alternatives.

Methods: This was an observational, multicenter, ambispective study of RRMM treated with or without a mAb.

Results: A total of 171 patients were included.

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Article Synopsis
  • A phase III trial with 286 multiple myeloma patients explored the effects of adding clarithromycin to the lenalidomide and dexamethasone (Rd) treatment.
  • * Despite a higher complete response rate in the clarithromycin group (C-Rd), no significant difference in progression-free survival (PFS) was found between the two treatment arms.
  • * The addition of clarithromycin resulted in more toxic deaths, suggesting that it did not provide significant benefits and may have led to increased side effects in this patient population.
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