Was Alpha deadlier than wild-type COVID? Analysis in rural England.

Background: It is useful to document whether each newly dominant SARS-CoV-2 variant of concern was more or less dangerous than preceding dominant variant(s). We assessed if the emergence of the Alpha (B.1.

Effective diabetes complication management is a step toward a carbon-efficient planet: an economic modeling study.

Background: The management of diabetes-related complications accounts for a large share of total carbon dioxide equivalent (COe) emissions. We assessed whether improving diabetes control in people with type 2 diabetes reduces COe emissions, compared with those with unchanging glycemic control.

Methods: Using the IQVIA Core Diabetes Model, we estimated the impact of maintaining glycated hemoglobin (HbA) at 7% (53 mmol/mol) or reducing it by 1% (11 mmol/mol) on total COe/patient and COe/life-year (LY).

Management of Patients With High Baseline Hip Fracture Risk by FRAX Reduces Hip Fractures-A Post Hoc Analysis of the SCOOP Study.

The Screening for Osteoporosis in Older Women for the Prevention of Fracture (SCOOP) study was a community-based screening intervention in women aged 70 to 85 years in the United Kingdom. In the screening arm, licensed osteoporosis treatments were recommended in women identified to be at high risk of hip fracture using the FRAX risk assessment tool (including bone mineral density measurement). In the control arm, standard care was provided.