Publications by authors named "Rianne van den Ham"

To ensure equitable access to medicines and vaccines, organizational efforts and purchase volumes have been pooled in joint procurements and negotiations for decades in some regions of the world, as well as globally through supranational procurement mechanisms. In Europe, countries started to collaborate on procurement and negotiations recently when it became increasingly difficult to ensure access to high-priced medicines, even in high-income countries. Two European country collaborations (the Nordic Pharmaceutical Forum and the Baltic Procurement Initiative) have successfully concluded at least one joint tender process for medicines and vaccines and the Beneluxa Initiative has concluded its first successful joint price negotiation.

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Article Synopsis
  • The study examined how well healthcare providers adhere to the Summary of Product Characteristics (SmPC) for three direct oral anticoagulants (DOACs): dabigatran, rivaroxaban, and apixaban, across five European countries between 2008 and 2015.* -
  • A total of 407,576 patients were initiated on DOACs, with significant variations found in adherence to contraindications, special warnings, and drug interactions across different databases; for instance, contraindications varied from 8.2% to 55.7% among patients.* -
  • The most common indication for DOAC use was non-valvular atrial fibrillation, while "malignant neoplasm"
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