[Effects of interferon on hepatic intercellular adhesion molecule-1 expression in patients with chronic hepatitis B].

Objective: To investigate the effects of interferon -alpha1b (IFN-alpha1b) on hepatic intercellular adhesion molecule-1 (ICAM-1) expression and serum HBV DNA in patients with chronic hepatitis B.

Methods: Before and 6 months after IFN-alpha1b treatment, liver biopsy was performed in patients with chronic hepatitis B to detect the expression of ICAM-1 in the liver tissues using immunohistochemistry. Serum HBV load was detected with real-time fluorescence polymerase chain reaction.

[A clinical and pathological study of nonalcoholic fatty liver disease].

Objective: To study the pathological and clinical features of nonalcoholic fatty liver disease (NAFLD).

Methods: Grades and stages of liver lesions in 41 patients with NAFLD were analyzed. The relationships between pathohistological features of the livers, serum biochemical parameters, ultrasound examination and other clinical data of the patients were studied.