Publications by authors named "Rhys A Slough"

Background: Methods for accurate quantification of lung fluid in heart failure (HF) are needed. Dynamic contrast-enhanced (DCE)-MRI may be an appropriate modality.

Purpose: DCE-MRI evaluation of fraction of fluid volume in the interstitial lung space (v ) and vascular permeability (K ).

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Purpose: The primary objective was to compare T2-FRFSE and T2-PROPELLER sequences for image quality. The secondary objective was to compare the ability to detect prostate lesions at MRI in the presence and absence of motion artefact using the 2 sequences.

Methods: 99 patients underwent 3 T MRI examination of the prostate, including T2-FRFSE and T2-PROPELLER sequences.

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Facilitating clinical translation of quantitative imaging techniques has been suggested as means of improving interobserver agreement and diagnostic accuracy of multiparametric magnetic resonance imaging (mpMRI) of the prostate. One such technique, magnetic resonance fingerprinting (MRF), has significant competitive advantages over conventional mapping techniques in terms of its multi-site reproducibility, short scanning time and inherent robustness to motion. It has also been shown to improve the detection of clinically significant prostate cancer when added to standard mpMRI sequences, however, the existing studies have all been conducted on 3.

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Objective: To introduce capped biparametric (bp) MRI slots for follow-up imaging of prostate cancer patients enrolled in active surveillance (AS) and evaluate the effect on weekly variation in the number of AS cases and total MRI workload.

Methods: Three 20 min bpMRI AS slots on two separate days were introduced at Addenbrooke's Hospital, Cambridge. The weekly numbers of total prostate MRIs and AS cases recorded 15 months before and after the change (Groups 1 and 2, respectively).

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Objective: To compare image quality, artefact, and distortion in standard echo-planar imaging (EPI) with periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) for prostate magnetic resonance imaging (MRI) diffusion-weighted imaging (DWI) in patients with previous total hip replacement (THR).

Methods: 21 male subjects with a clinical suspicion for, or known prostate cancer and previous THR were scanned at 1.5 T using a phased-array body coil.

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Objective: To prospectively investigate the longitudinal effect of ejaculatory abstinence on MRI-measured seminal vesicle (SV) volume and whole-prostate ADC over consecutive days.

Methods: 15 healthy male volunteers (mean 35.9 years, range 27-53) underwent 3-T MRI at baseline and 1, 2 and 3 days post-ejaculation.

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Purpose: To evaluate the effect of rectal distension on the quality of anatomical and functional prostate multiparametric (mp) MRI.

Materials And Methods: Multiparametric (mp) 3T-MRI images of 173 patients were independently evaluated by two radiologists in this retrospective study. Planimetry rectal volumes were derived and a subjective assessment of rectal distension was made using a 5-point Likert scale (1=no stool/gas, 5=large amount of stool/gas).

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Synopsis of recent research by authors named "Rhys A Slough"

  • - Rhys A Slough's research focuses primarily on the application and validation of advanced magnetic resonance imaging (MRI) techniques, particularly in assessing prostate health and heart failure conditions, enhancing both image quality and diagnostic accuracy.
  • - Key findings from his studies include comparisons of MRI sequences for optimal lesion detection, reproducibility of T1 mapping in prostate imaging, and the impact of various preparations on MRI outcomes, highlighting specific techniques such as T2-PROPELLER and magnetic resonance fingerprinting.
  • - Additionally, Slough's work addresses practical aspects of MRI workload management and patient outcomes by analyzing the effects of protocol changes in clinical settings, contributing to evidence-based practices in radiology concerning prostate cancer surveillance and heart failure assessments.