Publications by authors named "Rhea O Regan"
Objectives: Periprosthetic joint infection (PJI) is a complication of joint arthroplasty and is seen in 1-2% of cases. Since its initiation in 2013, the national outpatient parenteral antimicrobial therapy (OPAT) program has facilitated the outpatient management of intravenous antimicrobials for PJI. This study aims to describe the clinical epidemiology of patients on OPAT with PJI between 2013 and 2021.
View Article and Find Full Text PDFIn this study, we aim to describe the demographic, clinical and imaging characteristics, treatment course and subsequent outcomes of the first 116 cases presenting to a tertiary Dublin hospital with COVID-19 infection and to compare whether ethnic minority background was a risk factor for poorer disease outcomes in this cohort. Of 116 cases analysed, 100 (86%) patients presented from the community, 6 (5%) from care homes and 10 (9%) were existing inpatients. Fifty-four (46%) patients identified as being from an ethnic minority group.
View Article and Find Full Text PDFBackground: While the modes of transmission of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) are well studied, the risk of transmission in various group settings or activities is less clear. This living scoping review aims to summarize the risk factors of coronavirus disease 2019 (COVID-19) spread in common group activities (e.g.
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- - The study investigated the accuracy and effectiveness of various Rapid Antigen Detection Tests (RADTs) for SARS-CoV-2, comparing them to the standard RT-PCR tests, and examined different testing strategies and settings.
- - After reviewing 8010 records, 18 studies were included in the analysis, showing that while RADTs had high specificity (>98%), sensitivity varied, particularly favoring samples collected by healthcare workers over self-collected ones, and nasal samples performed better than saliva.
- - The researchers concluded that more high-quality studies are needed to validate the findings, as the current literature showed a risk of bias and differences in sensitivity, and recommended evaluating testing strategies in real-world scenarios focusing on transmission and incidence rates.
We describe the development of a risk assessment profile tool that incorporates data from multiple domains to help determine activities and events where rapid antigen detection tests (Ag-RDT) could be used to screen asymptomatic individuals to identify infectious cases as an additional mitigation measure to reduce transmission of SARS-CoV-2. The tool aims to stratify, in real time, the overall risk of SARS-CoV-2 transmission associated with common activities and events, and this can be matched to an appropriate Ag-RDT testing protocol.
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- Non-invasive respiratory support (NRS) has been crucial in treating COVID-19 pneumonia outside of intensive care units (ICUs).
- There is limited information available to help determine the best type of NRS to use for patients.
- This study examines the results of using NRS outside the ICU and explores how it impacts gas exchange, which is important for patient management.
Introduction: Our hospital found itself at the epicentre of the Irish COVID-19 pandemic. We describe the organisational challenges faced in managing the surge and identified risk factors for mortality and ICU admission among hospitalised SARS-CoV-2-infected patients.
Methods: All hospitalised SARS-CoV-2 patients diagnosed between March 13 and May 1, 2020, were included.
Aims: The Scottish Inpatient Diabetes Foot Audit conducted in 2013 revealed that 57% of inpatients had not had their feet checked on admission, 60% of those at risk did not have pressure relief in place and 2.4% developed a new foot lesion. In response, the Scottish Diabetes Foot Action Group launched the 'CPR for Feet' campaign.
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