Utilization of Chimeric Antigen Receptor T-cell Therapy in Adults.

Objective: To discuss the mechanism of action and nursing care of adults receiving chimeric antigen receptor (CAR) T-cell therapy.

Data Source: Peer reviewed articles and pharmaceutical drug labels.

Conclusion: CAR T-cell therapy is among the most exciting therapies in the evolution of cancer treatment.

Management Principles Associated With Cytokine Release Syndrome.

Objective: To discuss current recommendations and resources for nurses to ensure they advocate for patients with cytokine release syndrome (CRS).

Data Sources: A literature search using key terms: cytokine release syndrome, neurotoxicity, CAR T, adverse events.

Conclusion: Chimeric antigen receptor (CAR) T-cell immunotherapy is a growing and rapidly changing field of research.