[Correction of disorders of the system of blood aggregation regulation by ionol in the post-resuscitation period].

In the experiments on white rats resuscitated after a 7-minute mechanical asphyxia, phase disorders in the indices of the system of regulation of aggregate state of the blood in postresuscitation period have been revealed. They appear in the shape of a syndrome of disseminated intravascular blood coagulation with the development of hypercoagulation phase by the 3rd hour. Prophylactic introduction of ionol in a dose of 100 mg/kg in 48, 24 and 1 hour before the experiment prevents the development and progressing of the above syndrome.

[Pulmonary microcirculatory bed and alveolar tissue in the postresuscitation period].

Structural changes in alveolar lung tissue microcirculatory bed and circulatory disturbances (edema, hemorrhage, thrombosis) were studied in postresuscitation period after experimental clinical death following acute hemorrhage and mechanical asphyxia. Circulatory disturbances proved essential in the pathogenesis of postresuscitation respiratory insufficiency, follow a stepwise pattern and in early postresuscitation (up to 7 days) are pathogenetically associated with coagulopathic changes. There are periods of primary, marked and delayed disturbances, and the period of reparative changes which may cover up to 30 days since resuscitation.

[Two cases of Ostertagia spp. in sheep showing resistance to benzimidazole anthelmintics].

Two field isolates of Ostertagia spp. of sheep from the Swellendam and Malmesbury districts in the south-western Cape were shown to be resistant to benzimidazole anthelmintics. At therapeutic dosage rates albendazole was 32,5%, thiabendazole 0%, oxfendazole 14,9% and morantel 91,4% effective against the adult stage of Ostertagia spp.

The effects of reducing frequency of negative thoughts on the mood of depressed patients-tests of a cognitive model of depression.

Cognitive theories of depression propose that depressed mood is caused by depressing cognitions (negative thoughts). In two studies of depressed patients, presentation of external information at a high rate was used to reduce the frequency of negative thoughts, and the subsequent effect on depressed mood examined. Single-case designs were employed in both studies.