Joint Associations of Sedentary Time and Intensity-Specific Physical Activity With Cancer Mortality: A Device-Based Cohort Study of 72,458 UK Adults.

Background: There are no studies examining the prospective joint association of device-based measures of sedentary time and physical activity (PA) with cancer mortality. We examined the joint associations of sedentary time and intensity-specific PA with cancer mortality in 72,458 adults from UK Biobank.

Methods: Participants wore an Axivity AX3 accelerometer on their dominant wrist for at least 3 days (with at least 1 weekend day).

Association between lifestyle risk factors and mortality in the Mexico City prospective study.

Unhealthy lifestyles risk factors, such as smoking, alcohol consumption, physical inactivity, poor diet, and obesity, have been associated with a higher risk of all-cause and cause-specific mortality. However, composite score of these unhealthy behaviours has not been considered, particularly in Latin American populations. Herein, we examined the association of lifestyle risk factors score with all-cause and cause-specific mortality in Mexican adults.

Combined association of physical activity and depressive symptoms with cardiometabolic risk factors in Chilean adults.

Cardiometabolic risk factors such as obesity, raised blood pressure, high blood glucose and dyslipidemia are emerging health concerns worldwide. Therefore, the aim of this study was to estimate the combined association between physical activity and depressive symptoms with cardiometabolic risk factors in Chilean adults. Data was obtained from the National Health Survey of Chile 2016-2017, with a sample of 5995 adult participants.

K. Koch in the Treatment of Skin Inflammation: A Comprehensive Evaluation of Its Therapeutic Properties.

is a plant widely cultivated for food and medicinal purposes. species have been reported as anti-inflammatory, antibacterial, anxiolytic, and antinephritic agents. This study aimed to evaluate the anti-inflammatory potential of the ethanolic extract (EE) from the aerial parts of and its most promising fraction in models of acute and chronic inflammation, including a psoriasis-like mouse model.

Persistent Median Artery and Carpal Tunnel Syndrome: A Retrospective Study.

 This study presents a retrospective study of persistent median artery associated with carpal tunnel syndrome (CTS).  A retrospective study of the persistent median artery and CTS. Exclusion criteria were patients who did not present persistent median artery, those who were diabetic, or had rheumatoid diseases, and those who decided not to do the surgery.

Intrauterine exposure to a high-fat diet, with different levels of lipids, and its gastrointestinal repercussions: a model of fetal programming in rats.

It is known that adverse stimuli, such as altered diets during pregnancy and lactation can result in deleterious effects on the progeny. The aim of this study was to evaluate the possible gastrointestinal repercussions in the offspring of Wistar rats exposed to high-fat diets. Pregnant rats were divided into three groups: normolipidic diet (3.

Identification of Novel Human 15-Lipoxygenase-2 (h15-LOX-2) Inhibitors Using a Virtual Screening Approach.

The human 15-lipoxygenase-2 (h15-LOX-2) catalyzes mainly the regio- and stereospecific oxygenation of arachidonate to its corresponding hydroperoxide (15()-HpETE). h15-LOX-2 is implicated in the biosynthesis of inflammatory lipid mediators and plays a role in the development of atherosclerotic plaques, but it is still underexploited as a drug target. Here, to search for novel h15-LOX-2 inhibitors, we used a virtual screening (VS) approach consisting of shape-based matching, two-dimensional (2D) structural "dissimilarity", docking, and visual inspection filters, which were applied to a "curated" ZINC database (∼8 × 10 compounds).

Disseminated sporotrichosis with osteoarticular involvement in a patient with acquired immunodeficiency syndrome: a case report.

Sporotrichosis is caused by fungi belonging to the genus Sporothrix, and is generally acquired by traumatic inoculation. A 26-year-old man developed pustular lesions and a 6-kg weight loss after developing a lesion on his right hand 6 months previously. He was diagnosed with acquired human immunodeficiency syndrome (AIDS) and disseminated sporotrichosis cultures of bone and muscle biopsy and blood samples grew Sporothrix schenckii.

Autism Spectrum Disorder Association with Socioeconomic and Demographic Factors: A Case-Control Study.

Introduction: Autism spectrum disorder (ASD) is an early-onset neurodevelopmental disorder whose prevalence is constantly increasing.

Objective: The aim of the study was to investigate the association between ASD and socioeconomic and demographic factors of parents of children/adolescents in Northern Minas Gerais, Brazil.

Methods: A case-control study was carried out, consisting of 1,134 children/adolescents, 248 with ASD and 886 without ASD.

Transition towards cancer mortality predominance over cardiovascular disease mortality in Brazil, 2000-2019: a population-based study.

Background: Cardiovascular disease (CVD) and cancer are the first and second leading causes of death in Brazil and worldwide. However, an ongoing epidemiological transition in which cancer surpasses CVD has been observed in many high and middle-income countries. In this study, we provided a nationwide analysis of the transition towards cancer mortality predominance over CVD mortality in Brazil.

Educational actions conducted during the pandemic with primary health care professionals: a scoping review.

Objectives: to map the educational actions conducted with primary health care professionals during the COVID-19 pandemic.

Methods: a scoping review conducted in August 2023, which covered databases such as CINAHL, Medline, LILACS, IBECS, BDENF, and Web of Science. In total, 32 publications were analyzed through content analysis.

Chronic noncommunicable diseases and their associated factors in community health workers.

Objectives: To analyze the epidemiological profile of chronic noncommunicable diseases among community health workers and associated factors.

Methods: Cross-sectional study of community health workers in the city of Montes Claros, Minas Gerais, Brazil. Data were collected through a questionnaire designed to characterize demographic and socioeconomic profile, employment profile, self-reported presence of chronic noncommunicable diseases, and lifestyle habits.

Use of low-level laser therapy as an adjuvant therapy for phlebostatic lesions.

Low-intensity laser therapy (LILT) is commonly used as an adjuvant therapy for treating injuries. This integrative literature review was carried out in the MEDLINE, LILACS, CUMED, BDENF, SPORTDiscus, Dentistry & Oral Sciences Source, Academic Source and CINAHL databases. Among the inclusion criteria were: range from 2011 to 2021, in English, Portuguese and Spanish and any study, with the exception of preprints and books.

Time trends in hypertension and diabetes prevalence by body mass index categories in Brazilian adults from 2006 to 2023.

Aim: The prevalence of diabetes and hypertension according to body mass index (BMI) status in Brazilian adults has not been described yet. Herein, we aimed to identify the time trends in hypertension and diabetes, individually and combined (multimorbidity), by BMI in Brazilian adults.

Methods: In this time series cross-sectional study, we retrieved self-reported data from 806 169 adults between 2006 and 2023, using the Surveillance System of Risk and Protective Factors from Chronic Diseases by Telephone Survey (Vigitel).

Impact of an instructional team's feedback on an instructor's teaching practices in a Biology of Cancer course.

The effective implementation of evidence-based teaching (EBT) in large college courses benefits from the successful use of instructional teams. An instructional team's feedback allows instructors to act based on evidence of student learning, addressing students' needs. This feedback may be particularly important for novice instructors or experienced instructors teaching a class for the first time.

Exploring botulinum toxin's impact on masseter hypertrophy: a randomized, triple-blinded clinical trial.

The present study aimed to assess the effectiveness and functional adverse effects of a single and multiple injections of botulinum toxin A (BoNT-A) for masseter hypertrophy (MH). Twenty-six women complaining about lower third facial enlargement due to MH, received 75 U of BoNT-A (abobotulinum toxin) in each masseter muscles. After 3 months, patients were randomly assigned to receive a second treatment session of Saline Solution: (G1; n = 11) or BoNT-A: (G2; n = 12).

An assessment of Brazilian dentists' knowledge about tooth fragment reattachment: A cross-sectional study.

Background/aim: Crown fractures are common traumatic dental injuries and tooth fragment reattachment is a viable option for restoring a fractured tooth. The aim of this study was to assess the knowledge and experience of dentists in the Federal District regarding the tooth fragment reattachment technique for enamel and dentin fractures.

Materials And Methods: For the cross-sectional observational study, an electronic form was designed with objective and self-report questions for dentists.