Anti-tuberculosis have up set the out come of this disease, however undesirable effects principally hepatotoxicity remain of ten the ransom of this therapy success. 28 observations of hepatic toxicity in allergology pneumo service in military hospital of Tunisia during 5 years (1996-2001) among 321 tuberculosis. Hepatic toxicity is observed in 28 cases, 21 cytolytics, 3 cholostatics and 4 mixt.
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