Botulinum toxin injection versus lateral internal sphincterotomy for chronic anal fissure: a meta-analysis of randomized control trials.

Background: Anal fissures, tears in the epithelium of the anal canal that cause pain and bleeding, have a lifetime prevalence of 11%. While surgical treatments, such as lateral internal sphincterotomy are traditional, they pose postoperative complications. Recent studies investigated less invasive options involving botulinum toxin injection, showing promise with fewer adverse effects.

The p53/miRNA Axis in Breast Cancer.

One of the main health issues in the modern world is cancer, with breast cancer (BC) as one of the most common types of malignancies. Different environmental and genetic risk factors are involved in the development of BC. One of the primary genes implicated in cancer development is the p53 gene, which is also known as the "gatekeeper" gene.

Comparing postoperative pain relief: ketorolac and Nasocalcin spray versus lidocaine and Nasocalcin spray in abdominal surgery patients.

Objectives: Postoperative pain management is critical for patient recovery after abdominal surgery. This study compared intravenous lidocaine and ketorolac for reducing postoperative pain and opioid use, along with Nasocalcin nasal spray.

Methods: In this randomized controlled trial, 58 abdominal surgery patients were allocated to receive either intravenous lidocaine plus Nasocalcin spray (=29) or intravenous ketorolac plus Nasocalcin spray (=29) before surgery.

Investigating the risk factors for isthmocele development after cesarean delivery.

Background: Cesarean delivery rates are increasing globally, raising concerns about associated complications such as isthmocele. Isthmoceles are pouch-like defects in the anterior uterine wall at the site of a prior cesarean delivery scar.

Objective: This study aimed to determine isthmocele prevalence, associated symptoms, and risk factors among women with a history of cesarean delivery.

Therapeutic Effect of Silver Nanoparticles in the Management of Diabetic Ulcers: A Systematic Review and Meta-Analysis on RCTs.

Aims: The skin, as the body's largest organ, plays vital roles in sensory functions, temperature regulation, and protection against pathogens and injuries. Skin wounds, which disrupt its integrity, can result from various factors, including diseases such as diabetes. Diabetic foot ulcers are a severe complication of diabetes, often leading to amputations.

Diagnostic value of enhanced-contrast ultrasound for cesarean scar pregnancy: A systematic review.

Background: Cesarean scar pregnancy, an uncommon ectopic pregnancy in which the embryo is implanted in the cesarean scar, poses significant risks without prompt diagnosis and treatment. Its prevalence has risen alongside increased cesarean section rates. Despite various treatment approaches, consensus remains elusive.

A Deep Learning Method for Near-Real-Time Cloud and Cloud Shadow Segmentation from Gaofen-1 Images.

In this study, an essential application of remote sensing using deep learning functionality is presented. Gaofen-1 satellite mission, developed by the China National Space Administration (CNSA) for the civilian high-definition Earth observation satellite program, provides near-real-time observations for geographical mapping, environment surveying, and climate change monitoring. Cloud and cloud shadow segmentation are a crucial element to enable automatic near-real-time processing of Gaofen-1 images, and therefore, their performances must be accurately validated.

Route of delivery as a risk factor for emergent peripartum hysterectomy: a case-control study.

Objective: To evaluate whether cesarean delivery is a risk factor for emergent postpartum hysterectomy.

Methods: We performed a case-control study of patients who delivered at Women & Infants Hospital between January 1989 and February 2000. Fifty cases of emergent postpartum hysterectomy performed within 14 days of delivery met our inclusion criteria.