Depression is a multifaceted mental health disorder with complex etiology and significant global burden. Recent research indicates that the gut microbiota plays a role in the pathophysiology of depression, highlighting the potential role of specific bacterial species in influencing mood and cognitive function. In this study, we aimed to investigate the presence, copy numbers, and Ct values of selected bacterial species in stool samples from depressed patients (n=50) compared to control subjects (n=50).
View Article and Find Full Text PDFBackground: Behavioral activation has gained increasing attention as an effective treatment for depression. However, the effectiveness of Behavioral Activation Group Therapy (BAGT) in controlled conditions compared to its self-help programs requires more investigation. The present study aimed to compare their effectiveness on depressive symptoms, repetitive negative thinking (RNT), and performance in patients with major depressive disorder (MDD).
View Article and Find Full Text PDFObjective: This study aims to compare the effectiveness of cognitive-behavioral therapy (CBT) and low-frequency (LF) repetitive transcranial magnetic stimulation (rTMS) in reducing symptom severity and depression and improving working memory in adults with obsessive-compulsive disorder (OCD).
Methods: This is a randomized clinical trial conducted on 24 adults with OCD, randomly assigned into two groups of CBT ( = 12, received CBT with exposure and response prevention (ERP) individually at 20 sessions) and rTMS ( = 12, received LF (1-Hz) rTMS over the right dorsolateral prefrontal cortex (DLPFC) at 10 sessions). They completed the Yale-Brown Obsessive Compulsive Scale, the Hamilton Depression Rating Scale, and two N-Back tasks before, immediately, and 1 month after interventions.
An emergence of mental health issues among the general population has been reported during the COVID-19 pandemic. This study aimed to estimate COVID-19 awareness, attitude, and perceived anxiety among the Iranian people. This is a cross-sectional web-based survey done on the community population of Iran.
View Article and Find Full Text PDFIntroduction: Generalized Anxiety Disorder (GAD) is one of the most common anxiety disorders that has significant adverse effects on social functioning, occupational/academic performance, and daily living. This study aimed to evaluate the effect of Quantitative Electroencephalography (QEEG)-based Neurofeedback (NFB) therapy on anxiety, depression, and emotion regulation of people with GAD.
Methods: This research is a quasi-experimental study with a pre-test/post-test/follow-up design and a control group.
Introduction: Today, addiction to opioids is a serious problem all over the world. Unfortunately, the consumption of these drugs and the number of addicted people have drastically increased. This research aimed at comparing the efficacy of anodal, cathodal, and sham transcranial Direct Current Stimulation (tDCS) on the Brain-Derived Neurotrophic Factor (BDNF) and psychological symptoms in opioid-addicted patients.
View Article and Find Full Text PDFPurpose: This study was conducted to determine the effect of training based on Bandura's Self-Efficacy Theory on sexual function and sexual satisfaction in newlywed women.
Methods: This randomized controlled trial was conducted on 96 newlywed women presenting to health centers in Zanjan, Iran, in 2016. The participants were assigned to an intervention and a control group using randomized blocking.