Publications by authors named "Reza Esmaeelzadeh Dizaji"

Malaria is the most pernicious parasitic infection, and is the most virulent species with substantial morbidity and mortality worldwide. The present in silico investigation was performed to reveal the biophysical characteristics and immunogenic epitopes of the 14 blood-stage proteins of the using comprehensive immunoinformatics approaches. For this aim, various web servers were employed to predict subcellular localization, antigenicity, allergenicity, solubility, physicochemical properties, posttranslational modification sites (PTMs), the presence of signal peptide, and transmembrane domains.

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Article Synopsis
  • Gastrointestinal issues in poultry, particularly in Iran, are often caused by various factors, including viruses like avian picornaviruses, which can lead to diarrhea.
  • In this study, researchers isolated and identified two genera of picornaviruses, Sicinivirus A (SiV A) and Megrivirus C (MeV C), from fecal samples of affected broiler chickens in Gilan province.
  • The findings suggest that simultaneous infections of different picornavirus genera in Eastern flocks may lead to increased genetic recombination, which could diversify gastrointestinal diseases in poultry; this is the first complete genomic report of these viruses in Iran.
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In September 2017, an outbreak with high mortality, which showed the typical signs of ND, occurred among a flock of more than 2000 Eurasian collared doves in Konarak, southeast of Iran. A confirmed pigeon paramyxovirus type 1 strain was isolated from the brain tissues of the dead doves. The isolate, which was called Pigeon/Iran/Konarak/Barin/2017, was classified as a highly velogenic NDV.

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Article Synopsis
  • The study investigates a cyclo-zoonotic infection caused by tapeworms and aims to analyze genetic diversity using mitochondrial genome data.
  • Researchers collected 52 tissue samples from patients in Iran over a span of 23 years, amplifying DNA to identify different genotypes through sequencing.
  • Findings revealed that the G1 genotype was most common, while the G3 genotype (Buffalo strain) was also present, enhancing understanding of the parasite’s transmission and genetic variation in Northern Iran.
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Newcastle disease (ND) is one of the most serious infectious and contagious viral diseases in avian species. Recently, several ND outbreaks in pigeon caused by pigeon paramyxovirus serotype-1 (PPMV-1) have been reported from Iran, but unfortunately, phylogenetic studies have been mostly conducted on partial sequence of NDV fusion (F) gene. In addition, a complete genome data of Iranian PPMV-1 strains are not available.

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Background: Antibiotics have long been the first line of defense to prevent Escherichia coli infections, but they have lost their potency since bacteria have grown increasingly resistant to treatment. The present research aimed to study the drug resistance and the prevalence of tetracycline resistance genes in E. coli isolated from broilers with colibacillosis.

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Fowl adenoviruses D and E (FAdV-D and E) can cause inclusion body hepatitis (IBH) in commercial chicken flocks. Recently, IBH outbreaks have been increasingly reported in different regions of Iran, particularly in broiler farms. The present study was conducted to perform, for the first time, a complete genome characterization of a FAdV isolate from an IBH outbreak in Iran.

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The coronavirus avian Infectious bronchitis virus (IBV) poses economic threats to poultry farms worldwide, affecting the performance of both meat-type and egg-laying birds. To define the evolution of recent IBVs in Iran, a genetic analysis based on hypervariable nucleotide sequences of S1 gene was carried out. Tracheal swab samples were collected from 170 Broiler flocks during 2017.

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Human echinococcosis is an infectious disease caused by tapeworms belonging to the species Echinococcus. This parasite has a worldwide distribution and is considered a neglected tropical disease by the World Health Organization. Due to the diversity of Echinococcus spp.

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