Publications by authors named "Reza Bahar"
A zoonotic disease called brucellosis can cause flu-like symptoms and heart inflammation. The bacteria responsible for this disease can also enter the brain, causing a condition called neurobrucellosis that can result in long-term neurological problems. In this study, researchers aimed to determine the changes in the hippocampal cells of rats infected with Brucella.
View Article and Find Full Text PDFBromelain is a plant-based molecule with antioxidant, antithrombotic, anticancer, and anti-inflammatory properties. Bromelain has been shown to reduce the release of inflammatory cytokines. This study aimed to determine whether bromelain can prevent ataxia in rats caused by 3-acetylpyridine (3-AP).
View Article and Find Full Text PDFArticle Synopsis
- Huntington's disease is a genetic disorder characterized by the progressive degeneration of brain nerve cells, leading to motor and cognitive issues, with no definitive cure available yet.
- A study tested the drug Apelin-13 on male Wistar rats with a Huntington’s disease model to see if it could help improve symptoms and reduce inflammation.
- Results showed that Apelin-13 treatment enhanced motor function, increased neuronal density, reduced inflammation, and improved overall brain health in the rats.
Huntington's disease (HD) is a hereditary condition characterized by the gradual deterioration of nerve cells in the striatum. Recent scientific investigations have revealed the promising potential of Extracellular vesicles (EVs) as a therapy to mitigate inflammation and enhance motor function. This study aimed to examine the impact of administering EVs derived from human umbilical cord blood (HUCB) on the motor abilities and inflammation levels in a rat model of HD.
View Article and Find Full Text PDFArticle Synopsis
- Concerns about lisdexamfetamine (LDX), a drug for ADHD, include potential irreversible brain damage and impacts on the neuroendocrine system during development.
- A study on adult male rats found that LDX treatment resulted in decreased sperm motility, increased DNA fragmentation, and significantly lower testosterone levels.
- The study suggests prolonged LDX use may lead to poor sperm quality and harmful changes in testicular tissue, but further research is needed, especially in humans using LDX long-term.