The Rhyacophila fasciata Species Complex (Trichoptera: Rhyacophilidae) in Turkey with description of a new species, Rhyacophila anatolica Ekingen & Valladolid, sp. nov., based on morphological, genetic, and ecological evidence.

The morphology of the larva, pupa, male, and female of Rhyacophila anatolica Ekingen & Valladolid, sp. nov., from Turkey is described.

Comparative Efficacy of Microwave versus Radiofrequency Ablation in Hepatocellular Carcinoma: Systematic Review and Meta-Analysis of Randomized-Controlled Trials.

: Hepatocellular carcinoma (HCC) is a leading global cause of cancer-related deaths. Thermal ablation techniques, especially radiofrequency ablation (RFA) and microwave ablation (MWA), have become pivotal treatments for HCC. This systematic review and meta-analysis aim to compare these modalities, highlighting their efficacy, strengths, and limitations in treating HCC.

The Comparison of Serum Interleukin-8 Levels Based on Severity of Liver Cirrhosis.

Background: The molecule known as Interleukin-8 (IL-8), a chemotactic leukocyte, has been found to have a crucial role in the perpetuation of the inflammatory environment that is associated with hepatitis B virus (HBV) infection, as well as in the development of liver cirrhosis and cancer.

Objective: The aim of this study was to carefully examine the role of IL-8 in the inflammatory reaction and to compare the levels based on the severity of liver cirrhosis.

Methods: The study was conducted from February 2018 to September 2018 at the Gastroenterohepatology Division, Internal medicine Department, Faculty of Medicine, Universitas Sumatera Utara.

The Rhyacophila fasciata Species Complex (Trichoptera: Rhyacophilidae) in Central Europe with description of a new species, Rhyacophila loeffleri Valladolid & Waringer, n. sp., based on morphological, genetic and ecological evidence.

The morphology of the larva, pupa, male, and female of Rhyacophila loeffleri Valladolid & Waringer, n. sp., from Austria, Czech Republic, France, and Italy is described.

Study of the Molecular Dynamics Stability in the Inhibitory Interaction of Tenofovir Disoproxil Fumarate against CTLA-4 in Chronic Hepatitis B Patients.

Background: Tenofovir disoproxil fumarate (TDF) is a first-line nucleotide analog (NA) drug for hepatitis B therapy. Long-term NA therapy increases peripheral T cell levels to enhance antiviral response, while CTLA-4 inhibits the activation.

Objective: This study analyzed the interaction between TDF and CTLA-4 through molecular docking.

Association Between Serum Cytotoxic T Lymphocyte Antigen (CTLA)-4 Level and Disease Progression in Patients With Chronic Hepatitis B.

Backgroud: Immune impairment, marked by increased expression of cytotoxic T lymphocyte antigen (CTLA)-4, promotes the disease progression of chronic hepatitis B.

Objective: This study aimed to determine the association between serum CTLA-4 level and disease progression in patients with chronic hepatitis B.

Methods: A cross-sectional study was conducted at Haji Adam Malik General Hospital Medan, Indonesia between October 2021 to September 2022.

PH negative acute lymphoblastic leukemia in adolescents and young adults treated according a MRD adapted BFM ALL IC 2009 protocol: Argentine real-world data on 171 patients.

Intensified pediatric chemotherapy regimens to treat adolescents and young adults (AYA) patients with Philadelphia negative acute lymphoblastic leukemia (ALL) have been associated with better outcomes. The local BFM 2009-based scheme complements the risk stratification assessing the measurable residual disease (MRD) along the induction phase with increasing levels of sensitivity. The present retrospective multicenter analysis included 171 AYA (15-40 years) patients treated accordingly between 2013 and 2019.

The Rhyacophila fasciata Group in Europe: Rhyacophila macedonica Karaouzas, Valladolid amp; Ibrahimi (n. sp.) from Greece, Kosovo, Republic of North Macedonia and Serbia (Trichoptera: Rhyacophilidae).

The morphology of all postembryonic stages (larva, pupa, male, and female) of Rhyacophila macedonica Karaouzas, Valladolid, Ibrahimi n. sp. from Greece, Republic of North Macedonia, Kosovo and Serbia was examined.

Prevalence of Aspergillus-Derived Mycotoxins (Ochratoxin, Aflatoxin, and Gliotoxin) and Their Distribution in the Urinalysis of ME/CFS Patients.

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a known complex, multi-organ system disorder with a sudden or subacute onset. ME/CFS occurs most commonly among women between 30 and 50 years of age. The current diagnostic criteria of ME/CFS, as defined by the Centers for Disease Control and Prevention, includes: profound fatigue and post-exertional malaise (>6 mo) unrelieved by rest, persistent cognitive impairment or orthostatic intolerance, and chronic unrefreshing sleep.

Association Between Serum IL-6, IL-10, IL-12, and IL-23 Levels and Severity of Liver Cirrhosis.

Background: Liver cirrhosis contributes to high liver-related mortality globally. Systemic inflammation mediated by immune cells contributes to the progression of liver cirrhosis. Growing evidence shows that several pro- and anti-inflammatory cytokines might have an important role in liver cirrhosis.

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Essentials of Diagnosis and Management.

Despite myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) affecting millions of people worldwide, many clinicians lack the knowledge to appropriately diagnose or manage ME/CFS. Unfortunately, clinical guidance has been scarce, obsolete, or potentially harmful. Consequently, up to 91% of patients in the United States remain undiagnosed, and those diagnosed often receive inappropriate treatment.

Clinical characteristics and evolution of hematological patients and COVID-19 in Argentina: a report from the Argentine Society of Hematology.

Individuals with malignancies and COVID-19 have a lower survival compared with the general population. However, the information about the impact of COVID-19 on the whole hematological population is scarce. We aimed to describe the 30th day overall survival (OS) after COVID-19 infection in patients with a hematological disease in Argentina.

The Rhyacophila fasciata Group in Europe: Rhyacophila fasciata Hagen 1859 and formerly synonymized species (Trichoptera: Rhyacophilidae), with new description of Rhyacophila fasciata and Rhyacophila septentrionis McLachlan 1865 (stat. prom.).

The presence and distribution of Rhyacophila fasciata Hagen 1859 in Europe were revised, based on bibliographic study, collection specimens, and new material collected in different countries. The status of formerly synonymized species, Rhyacophila ferruginea (Scopoli 1763) and Rhyacophila septentrionis McLachlan 1865 was also assessed. The type of R.

The Rhyacophila fasciata Group in Croatia and Bosnia and Herzegovina: Rhyacophila f. fasciata Hagen 1859 and the description of two new subspecies, Rhyacophila fasciata delici Kučinić Valladolid (ssp. nov.) from Croatia and Bosnia and Herzegovina and Rhyacophila fasciata viteceki Valladolid Kučinić (ssp. nov.) from Bosnia and Herzegovina (Trichoptera: Rhyacophilidae).

We present the description of two new subspecies of the Rhyacophila fasciata Group: Rhyacophila fasciata delici Kučinić Valladolid (ssp. nov.), broadly distributed in Croatia and present also in Bosnia and Herzegovina, and R.

[Argentine Consensus in effective management of anticoagulation clinics for the use of vitamin k antagonists].

Treating an anticoagulated patient with vitamin K antagonists (VKA) remains a challenge, especially in areas where dicoumarins are still the first drug of choice due to the cost of other oral anticoagulants. Anticoagulation clinics have proven to be the most efficient and safe way to avoid thrombotic and hemorrhagic complications and to keep patients in optimal treatment range. However, they require adequate infrastructure and trained personnel to work properly.

Association between CD133 expression and clinicopathological profile in colorectal cancer.

Aim To investigate CD133 expression and its relationship to clinicopathological profile in colorectal cancer (CRC) patients. Methods This cross-sectional study was performed at the Internal Medicine Department, School of Medicine, Adam Malik General Hospital. The colorectal cancer tissue was taken from surgical resection and colonoscopy biopsy from CRC patients.

The Rhyacophila fasciata Group in Greece: Rhyacophila kykladica Malicky amp; Sipahiler 1993 (stat. prom.) (Trichoptera: Rhyacophilidae). Morphological description, genetic and ecological features.

The morphology of the different stages (larva, pupa, male, and female) of Rhyacophila fasciata kykladica Malicky Sipahiler 1993 was examined as a basis for the description of the taxon. Morphological data were supplemented by molecular analysis of mitochondrial cytochrome C oxidase subunit I (mtCOI), which were compared with samples of the nominate subspecies Rhyacophila fasciata fasciata Hagen 1859, as well as with other new species in this group, Rhyacophila denticulata McLachlan 1879 and Rhyacophila sociata Navás 1916. Our results revealed genetic differences between all the taxa; therefore, a change of taxonomic status of R.

Endoscopic Submucosal Dissection for Colitis-Associated Dysplasia.

Dysplasia is a precancerous lesion of colorectal cancer in patients with long-standing inflammatory bowel diseases (IBDs), such as ulcerative colitis and Crohn's disease. Recent guidelines suggest endoscopic resection as a key modality for the treatment of endoscopically resectable dysplasia in patients with colitis. Endoscopic submucosal dissection (ESD) has been suggested as one of the therapeutic options for dysplasia that is potentially resectable but not suitable for the conventional endoscopic mucosal resection technique.

The Rhyacophila fasciata Group in Western Europe: Confirmation of Rhyacophila denticulata McLachlan 1879 (stat. prom.) and Rhyacophila sociata Navás 1916 (stat. res.), based on morphological and molecular genetic evidence (Trichoptera: Rhyacophilidae).

In order to check the presence and distribution of Rhyacophila fasciata fasciata Hagen 1859 (species described from Austria) and R. fasciata denticulata McLachlan 1879 in the Iberian Peninsula, we studied the morphology of Spanish, French, and Austrian specimens, together with their mitochondrial cytochrome c oxidase (mtCOI). We observed that the individuals considered to date as R.

Biophysical Techniques to Study B Cell Activation: Single-Molecule Imaging and Force Measurements.

Cells of the adaptive immune system recognize pathogenic peptides through specialized receptors on their membranes. The engagement of these receptors with antigen leads to cell activation, which induces profound changes in the cell including cytoskeleton remodeling and membrane deformation. During this process, receptors and signaling molecules undergo spatiotemporal reorganization to form signaling microclusters and the immunological synapse.

Feasibility of Using Unbound Mixed Recycled Aggregates from CDW over Expansive Clay Subgrade in Unpaved Rural Roads.

Social awareness aims to increase practical skills, such as sustainable development, which seeks to increase the use of different types of waste in construction activities. Although insufficient attention is sometimes given to these actions, it is essential to spread information regarding new studies in the field of waste recycling, which encourages and promotes waste use. Reusing and recycling construction waste in the creation of buildings and infrastructure are fundamental strategies to achieving sustainability in the construction and engineering sectors.

The collection of Bathynellacea specimens of MNCN (CSIC) Madrid: microscope slices and DNA extract.

This is the first published database of a Bathynellacea Chappuis, 1915 collection of slices and DNA extracts. It includes all data of bathynellaceans (Crustacea: Syncarida) collected in the last 48 years (1968 to 2016) on the Iberian Peninsula and Balearic Islands, studied since 1984. It also includes specimens studied across many countries of Europe (Portugal, Romania, France, Italy, Slovenia, Bulgaria, and England), as well as some specimens obtained from samples of North America (Montana, Washington, Alaska and Texas), South America (Brazil, Chile and Argentina), Asia (China, Thailand, Vietnam, Mongolia and India), Africa (Morocco and Chad) and Australia (New South Wales -NSW- and Queensland).