Publications by authors named "Rex S Lott"

Objective: To review the pharmacology, pharmacokinetics, clinical use, and potential adverse effects of lamotrigine in elderly patients with epilepsy.

Data Sources: English-language literature regarding humans was searched from January 1990 through January 2003 using PubMed and the terms "lamotrigine," "epilepsy," and "elderly."

Study Selection: Studies of epilepsy treatment with lamotrigine in elderly patients, review articles, pharmacokinetic and pharmacodynamic studies, and clinical studies/reports regarding adverse effects of lamotrigine were evaluated.

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Study Objective: To assess patient tolerability and impact on institutional drug acquisition costs of converting patients from sustained-release bupropion to generic immediate-release bupropion.

Design: Retrospective medical record review.

Setting: Veterans Affairs medical center.

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