Publications by authors named "Rex Hamilton"

Purpose: To describe and evaluate a method for calculating intraocular lens (IOL) power in the second operative eye of patients with a history of keratorefractive surgery.

Methods: All eyes had undergone cataract surgery by a single surgeon from 2015 to 2018. Postoperative outcomes on the first eye (eg, IOL power implanted and postoperative refractive error) were used to back calculate a "Real K" for the first eye.

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Purpose: To compare uncorrected distance visual acuities (UDVAs) and induced higher-order aberrations (HOAs) in the early postoperative period between low-energy (LE) small-incision lenticule extraction (SMILE), high-energy (HE) SMILE, and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) procedures.

Setting: University based refractive surgery center.

Study Design: Retrospective cohort study.

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Patient satisfaction after modern day cataract surgery requires excellent surgical technique but increasingly demands superior refractive outcomes as well. In many cases, there exists an expectation from patients, as well as surgeons, to achieve emmetropia after cataract surgery. This is particularly true in patients electing premium intraocular lens technology to correct astigmatism and presbyopia to minimize spectacle dependence.

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As cataract surgery has evolved into lens-based refractive surgery, expectations for refractive outcomes continue to increase. During the past decade, advancements in technology have provided new ways to measure the cornea in preparation for cataract surgery. The increasing ability to accurately estimate corneal power allows determination of the most precise intraocular lens (IOL) for each patient.

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Purpose: To identify risk factors for opaque bubble layer (OBL) formation and compare the incidence of OBL using a cone modification technique versus the original technique for LASIK flap creation using the VisuMax laser (Carl Zeiss Meditec, Jena, Germany).

Methods: This retrospective study examined videos of flap creation using the VisuMax laser to identify OBL occurrence. Eyes were divided into three groups: eyes where OBL occurred using the original technique (OBL group), eyes where OBL did not occur using the original technique (no OBL group), and eyes in which the cone modification technique was used for LASIK flap creation (larger flap diameter) (cone modification technique group).

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Unlabelled: Presbyopia is the most common refractive disorder for people older than 40 years. It is characterized by a gradual and progressive decrease in accommodative amplitude. Many surgical procedures for the correction of presbyopia exist, with additional procedures on the horizon.

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Purpose: To evaluate the difference in corneal biomechanical waveform parameters between manifest keratoconus, forme fruste keratoconus, and healthy eyes with a second-generation biomechanical waveform analyzer (Ocular Response Analyzer 2).

Setting: Jules Stein Eye Institute, University of California, Los Angeles, California, USA.

Design: Retrospective chart review.

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Purpose: To determine the safety, efficacy, and predictability of combined astigmatic keratotomy (AK) and conductive keratoplasty (CK) for treating high corneal astigmatism.

Setting: University of California-Los Angeles, Los Angeles, California, USA.

Design: Retrospective case series.

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Purpose: To compare the prediction error after toric intraocular lens (IOL) (Acrysof IQ) implantation using corneal astigmatism measurements obtained with an IOLMaster automated keratometer and a Galilei dual rotating camera Scheimpflug-Placido tomographer.

Setting: Jules Stein Eye Institute, University of California Los Angeles, Los Angeles, California, USA.

Design: Retrospective case series.

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Purpose: To compare the variance in manifest refraction spherical equivalent (MRSE) after photorefractive keratectomy (PRK) with mitomycin-C (MMC), PRK without MMC, and laser in situ keratomileusis (LASIK) for the treatment of myopic astigmatism.

Setting: Jules Stein Eye Institute, University of California, Los Angeles, Los Angeles, California, USA.

Design: Retrospective case series.

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Femtosecond laser-assisted cataract surgery provides surgeons an exciting new option to potentially improve patient outcomes and safety. Over the past 2 years, 4 unique laser platforms have been introduced into the marketplace. The introduction of this new technology has been accompanied by a host of new clinical, logistical, and financial challenges for surgeons.

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Purpose: To report the use of annular amniotic membrane transplantation as a host incorporated graft in the management of Brown-McLean syndrome.

Methods: Case report.

Results: An 87-year-old man underwent annular amniotic membrane transplantation with ethylenediaminetetraacetic acid chelation resulting in resolution of pain, irritation, and foreign body sensation, and resolution of recurrent peripheral epithelial defects.

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Purpose: To compare the maximum posterior elevation (MPE) measurements before and after LASIK using a dual rotating Scheimpflug (DRS) imaging system (Galilei, Ziemer Ophthalmic Systems, Port, Switzerland) and a scanning slit-beam (SSB) imaging system (Orbscan IIz, Bausch & Lomb, Rochester, NY).

Methods: This retrospective study included 78 eyes from 78 patients who underwent myopic LASIK. Preoperative and postoperative data collected included anterior and posterior best-fit sphere radius and axial curvature readings, posterior central elevation (PCE), and MPE relative to a best-fit sphere using a 7.

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Purpose: To evaluate and compare corneal biomechanical waveform parameters between keratoconic and post-femtosecond laser in situ keratomileusis (LASIK).

Setting: Jules Stein Eye Institute, University of California, Los Angeles, California, USA.

Design: Comparative case series.

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Background And Objective: To identify the relationship between preoperative parameters and postoperative overcorrection or undercorrection in eyes with myopic astigmatism treated with wavefront-guided laser in situ keratomileusis (LASIK), and to develop an advanced surgical nomogram.

Patients And Methods: A retrospective chart review of 468 eyes that underwent wavefront-guided LASIK for myopia with astigmatism with the Alcon LADARVision 4000 (Alcon Laboratories, Fort Worth, TX), of which 235 had flaps created by microkeratome (OneUse; Moria Surgical, Doylestown, PA) and 233 by femtosecond laser (Intralase; AMO, Santa Ana, CA). Manifest sphere, cylinder, and spherical equivalent were recorded preoperatively and 3 months postoperatively.

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Purpose: To evaluate the difference in corneal biomechanical properties, after controlling for potentially confounding factors, along the spectrum of keratoconic disease as measured by the keratoconus severity score.

Methods: The corneal biomechanical properties of 73 keratoconic (KCN) eyes of 54 patients, 42 forme fruste keratoconic (FFKCN) eyes of 32 patients, and 115 healthy eyes of 115 age- and sex-matched patients were reviewed retrospectively. The main outcome measures were corneal hysteresis (CH) and corneal resistance factor (CRF).

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Purpose: To compare the effects of different flap creation techniques on the biomechanical properties of the cornea in patients having myopic laser refractive surgery.

Setting: UCLA Laser Refractive Center of the Jules Stein Eye Institute, Los Angeles, California, USA.

Methods: In this retrospective case series, eyes that had myopic laser refractive surgery were categorized according to the type of flap creation: mechanical microkeratome (MK) LASIK (n=32), femtosecond laser (FSL) LASIK (n=32), or no flap creation (PRK) (n=33).

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Purpose: To study the correlation between corneal biomechanical properties and surgical parameters in myopic patients before and after laser in situ keratomileusis (LASIK).

Setting: UCLA Laser Refractive Center of the Jules Stein Eye Institute, Los Angeles, California, USA.

Methods: In 43 eyes of 43 patients, the Ocular Response Analyzer was used to measure corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg), and corneal-compensated IOP (IOPcc) before and 1 month after LASIK.

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Purpose: To report recalcitrant unilateral epithelial ingrowth in two patients with ipsilateral weak eyelid closure.

Methods: Two patients with weak eyelid closure who underwent simultaneous, uncomplicated LASIK developed unilateral epithelial ingrowth.

Results: Eight months postoperatively, one patient presented with right-sided epithelial ingrowth.

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Purpose: To identify morphologic parameters obtained using scanning slit-beam topography that help distinguish normal from keratoconic corneal morphologic features.

Design: Observational, retrospective, cross-sectional study.

Methods: This retrospective review examined 207 normal eyes of patients undergoing an initial consultation for primary refractive surgery and 42 eyes with clinical keratoconus (KCN).

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As the number and types of keratorefractive procedures increase and as the baby boomer population moves into the "cataractous decades," the number of patients requiring cataract surgery following refractive surgery grows larger each year. While technological advances in surgical instrumentation and intraocular lens (IOL) design allow us to perform cleaner, faster, and more reliable cataract extractions, the ultimate postoperative refraction depends primarily on calculations performed before surgery. Third-generation IOL formulas ( Haigis, Hoffer Q, Holladay 2, or SRK/T) provide outstanding accuracy when used for eyes with physiologic, prolate corneas.

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