The effect of plasma treatment on the osseointegration of rough titanium implant: A histo-morphometric study in rabbits.

Abstract Background/purpose: The surface properties, such as hydrophilicity and functional OH groups, play an important role in bone fixation . In our previous study, the plasma treatments of large grit and acid etching (SLA) method produce functional OH groups on the rough surface. There is no report in discussing the integration between basic Ti-OH groups and bone-to-implant contact (BIC).

Surface Modification of Direct-Current and Radio-Frequency Oxygen Plasma Treatments Enhance Cell Biocompatibility.

The sand-blasting and acid etching (SLA) method can fabricate a rough topography for mechanical fixation and long-term stability of titanium implant, but can not achieve early bone healing. This study used two kinds of plasma treatments (Direct-Current and Radio-Frequency plasma) to modify the SLA-treated surface. The modification of plasma treatments creates respective power range and different content functional OH groups.

Effects of nanometric roughness on surface properties and fibroblast's initial cytocompatibilities of Ti6Al4V.

Titanium alloy (Ti6Al4V) has widespread medical applications because of its excellent biocompatibility. Its biological responses can further be enhanced by polishing and passivation. Unfortunately, preparing titanium alloy samples of nanometric roughness is by far much more difficult than preparing those of micrometric roughness, and numerous investigations on roughness induced effects are all focused on micrometric scales.