The feasibility of adjuvant interferon alpha-2b in children with high-risk melanoma.

Background: It has been shown that induction high-dose interferon alpha-2b (IFN-alpha-2b) followed by maintenance therapy improves recurrence-free survival in adults with high-risk, resected melanoma. In this study, the feasibility and toxicity of this regimen were evaluated in newly diagnosed pediatric patients with Stage III melanoma involving regional lymph nodes.

Methods: Fifteen patients age View Article and Find Full Text PDF

Topical imiquimod treatment for nodular basal cell carcinomas: an open-label series.

Background: Imiquimod has been used for basal cell carcinomas (BCCs). This is the first open-label series using imiquimod for nodular BCC with Mohs surgery resection for confirmation of treatment.

Objective: To evaluate the efficacy of topical imiquimod in patients with biopsy-proven nodular BCC.