Serous epithelial ovarian cancer, classified as either high-grade (90%) or low-grade (10%), varies in molecular, histological, and clinicopathological presentation. Low-grade serous ovarian cancer (LGSOC) is a rare histologic subtype that lacks disease-specific evidence-based treatment regimens. However, LGSOC is relatively chemo-resistant and has a poor response to traditional treatments.
View Article and Find Full Text PDFColorectal cancer (CRC) is the third most common type of cancer. One major pathway involved in the development of CRC is the serrated pathway. Colorectal polyps can be divided in benign, like small hyperplastic polyps and premalignant polyps, like the sessile serrated adenomas (SSA) that has a significant potential of malignant transformation.
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
September 2021
Objective: In women with cervical cancer (CC), treatment with radiation causes changes in vaginal biomechanical properties, anatomy and function. The aims of the current study were to objectively assess effects of radiotherapy (RT) on vaginal elasticity, wall mobility and contraction strength; and to evaluate associations of these changes with sexual function.
Study Design: This prospective cohort study was approved by our Institutional Review Board.
Purpose: We evaluated the effect of in vitro fertilization (IVF) on sexual function in men, particularly for erectile dysfunction.
Materials And Methods: A prospective case-control study at a tertiary medical center. The study group comprised men of infertile couples that required IVF to conceive.
Background And Objectives: Vaginal fractional carbon dioxide (CO ) laser treatment has emerged in the past two decades as a non-surgical option for vaginal tightening. Mounting evidence supports the effectiveness and safety of this treatment for female sexual dysfunction. A newly developed vaginal tactile imaging (VTI) technique accurately evaluates the biomechanical parameters of the female pelvic floor and vagina, including tissue elasticity, pelvic support, and pelvic muscle function in high definition.
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
July 2020
A 67-yr-old female patient was diagnosed with squamous cell vulvar carcinoma and treated with a radical vulvectomy and bilateral sentinel lymphadenectomy. Three months after the surgery, the patient presented with local recurrence and underwent surgical excision of the mass, followed by chemotherapy. Eight months later, the patient was admitted due to weakness and pleural effusion.
View Article and Find Full Text PDFJ Matern Fetal Neonatal Med
September 2020
The current meta-analysis evaluates the perinatal outcomes of twin pregnancies in pregnant women 35 years or older (advanced maternal age) compared with less than 35 years at the time of delivery. A search was conducted up to March 2018. Electronic databases that were used in our research included; Embase (NO Medline), Ovid Medline, Cochrane Central Register of Controlled Trials, and Web of Science.
View Article and Find Full Text PDFIntroduction: In about 85% of patients with primary hyperparathyroidism (pHPT) only a single parathyroid gland is diseased. The operation of choice in this group of patients is minimally invasive parathyroidectomy (MIP). In order to perform an MIP, the diseased gland should be identified prior to surgery.
View Article and Find Full Text PDFContext: Mixed adenoendocrine tumors of the extrahepatic bile ducts are exceedingly rare and most of those who are rarely diagnosed are adenocarcinomas. Neuroendorine tumors accounts for only 0.2-2%.
View Article and Find Full Text PDFContext: Pancreatic neuroendocrine tumors (PNETs) are rare tumors. These tumors are hypervascular in nature. Their surgical management is well described and practiced.
View Article and Find Full Text PDFA 32-year-old man presented to our department with abdominal pain and fever. In an earlier hospitalization he was diagnosed with periappendicular abscess and treated with antibiotics. Due to fever and 'non-resolution' of the abscess and due to its deep location in the lower abdomen, which excluded percutaneous drainage, we elected to operate the patient.
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