Dynamics of optical properties of sequentially diluted lucigenin aqueous solutions according to luminescence data.

The article discusses optical properties (luminescence) of diluted (24 dilution factor) lucigenin () aqueous solutions. Six series of aqueous solutions, with 50 samples in each series, were studied. The series were diluted on different days within random schedules, following a unified procedure: the first sample in all the series was the (C = 8.

Exceptional warming over the Barents area.

In recent decades, surface air temperature (SAT) data from Global reanalyses points to maximum warming over the northern Barents area. However, a scarcity of observations hampers the confidence of reanalyses in this Arctic hotspot region. Here, we study the warming over the past 20-40 years based on new available SAT observations and a quality controlled comprehensive SAT dataset from the northern archipelagos in the Barents Sea.

Synthesis of Silver Nanoparticles Using Reactive Water-Ethanol Extracts from .

Using the radiation-chemical simulation method of free radical reactions with 2,2-diphenyl-1-picrylhydrazyl, we were able to show high antiradical activity of water-ethanol extracts from . This will allow for the creation of new bioactive antioxidants based on them. The formation of silver nanoparticles (Ag-NP) was determined using the silver-ion reduction process by extracts.

Radiation Chemical Investigation of Antioxidant Activity of Biologically Important Compounds from Plant Materials.

Radiation chemical modeling of redox reactions of biologically active compounds from plant materials showed that coumarins possess strong antiradical properties. Data confirming the radioprotective properties of these compounds were obtained. Antioxidant activity has been shown for specific medicinal plant extracts- and cormus.

PEGylated ofloxacin nanoparticles render strong antibacterial activity against many clinically important human pathogens.

The rise of bacterial resistance against important drugs threatens their clinical utility. Fluoroquinones, one of the most important classes of contemporary antibiotics has also reported to suffer bacterial resistance. Since the general mechanism of bacterial resistance against fluoroquinone antibiotics (e.

Delivery as nanoparticles reduces imatinib mesylate-induced cardiotoxicity and improves anticancer activity.

Clinical effectiveness of imatinib mesylate in cancer treatment is compromised by its off-target cardiotoxicity. In the present study, we have developed physically stable imatinib mesylate-loaded poly(lactide-co-glycolide) nanoparticles (INPs) that could sustainably release the drug, and studied its efficacy by in vitro anticancer and in vivo cardiotoxicity assays. MTT (methylthiazolyldiphenyl-tetrazolium bromide) assay revealed that INPs are more cytotoxic to MCF-7 breast cancer cells compared to the equivalent concentration of free imatinib mesylate.

The Photovoltaic Effect of CdS Quantum Dots Synthesized in Inverse Micelles and R-Phycoerythrin Tunnel Cavities.

CdS quantum dots (CdS QDs) 4.3 nm in diameter synthesized in an AOT/isooctane/water microemulsion and in R-phycoerythrin tunnel cavities (3.5 × 6.

[Protection of Saccharomyces cerevisiae against oxidative and radiation-caused damage by alkyl hydroxybenzenes].

The effects of C7-alkylhydroxybenzene (C7-AHB) and p-hydroxyethylphenol (tyrosol), chemical analogs of microbial anabiosis autoregulators, on the viability of yeast cells under oxidative stress were investigated. The stress was caused by reactive oxygen species (ROS) produced under gamma irradiation of cell suspensions using doses of 10-150 krad at an intensity of 194 rad/s or by singlet oxygen generated in cells photosensibilized with chlorin e6 (10 micrograms/l). C7-AHB was found to exert a protective effect.

[The role of labile complexes with oxygen in antioxidant activity of carotenoids].

The present research work was done with the main purpose to study early stages of interaction of carotenoids (Car) with molecular oxygen and clarify their role in the mechanism responsible for Car radiochemical stability and carotenoid ability to decrease concentration of the most active oxygen transients like superoxide anion radicals (O2.-). Alcoholic and phosphate buffer (pH 7.

[Immunological mechanisms of the radioprotective effects of ceruloplasmin].

The aim of the work was to examine immunotropic features of celluroplasmine++ (Cp) and estimate its capacity as radioprotector. The pulse radiolysis method was used to set the mechanism of elementary reactions, which were responsible for antioxidant activity, and to demonstrate a particular role of reversible oxycomplexis, Cp..

[The behavior of inulin in aqueous solutions under exposure to gamma radiation].

Radiochemical transformations of inulin in aqueous solutions, in air, in the presence of inert gases, helium, nitrogen, and in nitrous oxide exposed to various doses of 60Co gamma irradiation were investigated. It was shown that interactions of inulin with OH radicals are principally responsible for radiolytic decomposition of inulin. The data on radiolysis of more simple model systems were used to make available decomposition of absorption spectra of gamma-irradiated aerated aqueous solution of inulin.

The mechanism of interaction of ceruloplasmin with superoxide radicals.

1. The mechanism of interaction of CP with O2- radicals in chemical and enzymatic systems of superoxide radical generation as well as in the pulse radiolysis technique was studied. 2.

The mechanism of interaction of carnosine with superoxide radicals in water solutions.

The antiradical activity and the radiation stability of carnosine in water solutions was studied by the pulse radiolysis technique with spectrophotometric registration of absorbance. The transient spectra were recorded in the range 245-670 nm during 2 x 10(-6)-20 s after the pulse using a flow system for continuous change and saturation of the samples by different gases. Also, the spectra of the stable products of radiolysis were studied.

[Interactions of carnosine and superoxide radicals in aqueous solutions].

Carnosine was discovered to be able to interact with superoxide-anion and active hydroxyl radicals, using carnosine aqueous solutions. This interaction is specific and can be detected at carnosine concentrations more than 0.02 mM.