Publications by authors named "Revathy Arushothy"
Article Synopsis
- The study investigates the burden of melioidosis in Malaysia, focusing on the epidemiological data and mortality rates linked to the disease.
- A retrospective review of data from the National Surveillance for Antibiotic Resistance (NSAR) between 2014 and 2020 showed an average annual incidence of 3.41 cases per 100,000 people, with significant variation across different states.
- Key risk factors identified include being of Malay ethnicity, diabetic, aged 40-49, and working in agriculture, particularly in areas like Pahang where the incidence was highest.
Background: Melioidosis is a neglected tropical disease with rising global public health and clinical importance. Melioidosis is endemic in Southeast Asia and Northern Australia and is of increasing concern in Malaysia. Despite a number of reported studies from Malaysia, these reports are limited to certain parts of the country and do not provide a cohesive link between epidemiology of melioidosis cases and the nation-wide distribution of the causative agent Burkholderia pseudomallei.
View Article and Find Full Text PDFThe emergence of non-vaccine multidrug-resistant Streptococcus pneumoniae serotypes is on rise. This study was performed to investigate a highly resistant serotype 15A S. pneumoniae isolated from the blood specimen of a 20-month-old patient who died of her infection.
View Article and Find Full Text PDFThis study was performed to investigate the serotype distribution and antimicrobial susceptibility of Streptococcus pneumoniae in Asian countries. A prospective surveillance study on S. pneumoniae collected from adult patients (≥50 years old) with invasive pneumococcal disease or community-acquired pneumonia was performed at 66 hospitals in Asian countries (Korea, China, Malaysia, Singapore, the Philippines, and Thailand) in 2012-2017.
View Article and Find Full Text PDFObjective: This study was performed to analyze the serotype distribution of Streptococcus pneumoniae causing invasive pneumococcal disease (IPD) in children aged 5 years and under in Malaysia and to assess the antimicrobial resistance.
Methods: From 2014 to 2017, a total of 245 invasive S. pneumoniae isolates from children ≤5 years of age were received from hospitals all around Malaysia.
After the introduction of the pneumococcal conjugate vaccine in Malaysia in recent years, the emergence of nonvaccine serotypes is of concern, particularly the antibiotic-resistant strains, with an increase specifically in serotype 15A. Here, we report the draft genome sequence of strain SS40_16, isolated from the blood sample of a 19-month-old female in 2016. SS40_16 is a multidrug-resistant strain with resistance to penicillin (MIC, ≥2 µg/ml), tetracycline, and trimethoprim-sulfamethoxazole.
View Article and Find Full Text PDFArticle Synopsis
- Legionella pneumophila are bacteria that can cause disease in humans, and their virulence is linked to specific genes.
- A study analyzed 33 isolates from cooling tower water to determine the presence of virulent gene regions (lvh and rtxA) using PCR.
- The findings revealed that 57.5% of the isolates had both genes, while others had variations in gene presence, indicating the importance of these genes in understanding the environmental prevalence of L. pneumophila in Malaysia.