Phage Targeting In Vitro and In Vivo as a Caries-Preventive Modality.

Dental caries is a common infectious disease worldwide. Current conventional therapies lack specific antimicrobial effects against , a key bacterium that induces caries. A promising alternative approach is bacteriophage (phage) therapy.

Isolation and Characterization of Phage as a Possible Treatment Agent for Caries.

is a key bacterium in dental caries, one of the most prevalent chronic infectious diseases. Conventional treatment fails to specifically target the pathogenic bacteria, while tending to eradicate commensal bacteria. Thus, caries remains one of the most common and challenging diseases.

The Israeli Phage Bank (IPB).

A key element in phage therapy is the establishment of large phage collections, termed herein "banks", where many well-characterized phages, ready to be used in the clinic, are stored. These phage banks serve for both research and clinical purposes. Phage banks are also a key element in clinical phage microbiology, the prior treatment matching of phages and antibiotics to specific bacterial targets.