Adoption of CKD-EPI (2021) for Glomerular Filtration Rate Estimation: Implications for UK Practice.

Introduction: Recommendations to move to a race-free estimating equation for glomerular filtration rate (GFR) have gained increasing prominence since 2021. We wished to determine the impact of any future adoption upon the chronic kidney disease (CKD) patient population of a large teaching hospital, with a population breakdown largely similar to that of England as a whole.

Methods: We compared four estimating equations (Modification of Diet in Renal Disease [MDRD], CKD-EPI [2009], CKD-EPI [2021], and European Kidney Function Consortium [EKFC]) using the Bland-Altman method.

The estimation of glomerular filtration in acute and critical illness: Challenges and opportunities.

Recent events have made it apparent that the creatinine based estimating equations for glomerular filtration have their flaws. Some flaws have been known for some time; others have prompted radical modification of the equations themselves. These issues persist in part owing to the behaviour of the creatinine molecule itself, particularly in acute and critical illness.

Living donor kidney transplantation: Let's talk about it.

Transplantation is the preferred treatment option for end-stage renal disease as it offers superior results and patient reported outcomes in comparison to dialysis. Patients treated with a transplant live longer, healthier and more independent lives. Transplantation is also more cost-effective, reducing the overall burden of renal disease.

An acute presentation of visceral artery aneurysm.

A 56-year-old patient presented with shock and severe abdominal pain. Initial blood tests, erect chest x-ray and focused ultrasound were not diagnostic. CT imaging demonstrated bleeding from a superior mesenteric artery aneurysm.