Antibacterial activity of soil-isolated complex against methicillin-resistant from Mwanza, Tanzania.

Unlabelled: Antimicrobial resistance in methicillin-resistant and beta-lactamase-producing Gram-negative bacteria is a global health concern necessitating research and the development of effective antimicrobial agents. This study, conducted in May 2020 in Mwanza, Tanzania, aimed to determine the antibacterial activity of metabolites from soil-isolated species against clinical bacterial pathogens. One soil-isolated species, identified as complex, showed antibacterial activity against Gram-positive cocci, including a methicillin-resistant strain with inducible clindamycin resistance, previously isolated from a patient with osteomyelitis.

Global Antimicrobial Resistance and Use Surveillance System on the African continent: Early implementation 2017-2019.

Background: Antimicrobial resistance (AMR) is becoming a critical public health issue globally. The World Health Organization launched the Global Antimicrobial Resistance and Use Surveillance System (GLASS) to support the strengthening of the AMR evidence base.

Objective: The article describes the evolution of national AMR surveillance systems and AMR data reporting of countries in the African continent between 2017 and 2019, and the constraints, perceived impact and value of the participation in GLASS.