Publications by authors named "Resti Mulyasari"
Asian Pac J Cancer Prev
April 2022
Article Synopsis
- The study aimed to systematically review and analyze the risk of acute myeloid leukemia (AML) transformation in adult patients with myelodysplastic syndrome (MDS), focusing on specific gene mutations.
- A comprehensive literature search identified 14 relevant articles, revealing that mutations in the SRSF2, DNMT3A, IDH, and RUNX1 genes were linked to an increased risk of AML transformation in these patients.
- The findings suggest that while some mutations (like U2AF1) do not significantly affect transformation risk, others notably increase the likelihood, indicating the importance of genetic profiling in MDS management.
