Molecular characterisation of mutations associated with resistance to first- and second-line drugs among Indonesian patients with tuberculosis.

Objectives: This study aimed to determine molecular characteristics of , and genes in isolated from a cohort of Indonesian patients with tuberculosis.

Methods: Fifty isolates of were analysed by testing (DST) for susceptibility to first- and second-line drugs using the proportional method in a liquid medium. The genomic material was extracted to perform multiplex polymerase chain reaction (PCR) for identification and gene sequencing of , and .