Unraveling Antiseizure Medication Adherence in Paediatric Epilepsy: Implications for Clinical Practice and Patient Care.

Objective: Non adherence to antiseizure medications (ASM) is a common and modifiable risk factor for poor control of epilepsy and contributes to increased hospitalizations, bias in assessing the effectiveness of therapy and inaccurate clinical decision making.The aim of the study was to estimate proportion of nonadherence to antiseizure medications among children with epilepsy and to identify clinical and demographic factors that contribute to antiseizure medication non adherence.

Methods: Consecutive subjects ≤ 18 years with epilepsy, on antiseizure medications for atleast three months, attending Pediatric Neurology OPD, Government Medical College Thiruvananthapuram, Kerala, India were included in the study.

Lower Extremity Osteoarthritis: Management and Challenges.

Osteoarthritis is the most common form of arthritis, a significant contributor to disability and the major cause for joint replacements, but treatment for the disease is still limited. Although no disease-modifying treatments exist, there are evidence-based algorithms and guidelines for the symptomatic treatment of the disease.