Publications by authors named "Reshmi Parameswaran"
Page 1 of 1
Synopsis of recent research by authors named "Reshmi Parameswaran"
- Reshmi Parameswaran's recent research extensively investigates natural killer (NK) cell mechanisms and their vital roles in cytotoxicity and dysfunction, particularly emphasizing the significance of p35 and O-GlcNAcylation in regulating NK cell function for therapeutic applications.
- The author has notably explored innovative strategies for targeting B cell cancers, including the development of a BAFF ligand-based chimeric antigen receptor (CAR) for enhanced therapeutic efficacy against malignant B cells, as well as investigating BAFF receptor-mediated therapies for mantle cell lymphoma and drug-resistant acute lymphoblastic leukemia.
- Her studies also highlight the metabolic vulnerabilities in acute myeloid leukemia (AML), identifying the hexosamine biosynthetic pathway and dietary lectins, like wheat germ agglutinin, as potential therapeutic targets, paving the way for novel treatment approaches in hematological malignancies.
