Publications by authors named "Reshma Soman"
Hypothyroidism is one of the most prevalent thyroid pathologies, which causes oxidative stress by disrupting antioxidant mechanisms. In mammals, the thyroid glands regulate metabolism, development, and growth. Dysfunction of the thyroid gland can result in hypothyroidism, hyperthyroidism, thyroiditis, and thyroid cancer.
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- In neurodegenerative diseases, proteins can form amyloids that damage neurons, and while some medications help with symptoms, they don’t address the underlying causes.
- This study focused on identifying new plant-based anti-amyloid agents by extracting and analyzing phytochemicals, leading to the discovery of 18 compounds from a medicinal plant.
- Several of these compounds demonstrated potential interactions with proteins involved in amyloid formation, and specific phytochemicals showed promising results in preventing or reducing amyloid buildup, warranting further investigation.
Among the diverse Vibrio spp. autochthonous to coastal ecosystems, V. cholerae, V.
View Article and Find Full Text PDFAcute promyelocytic leukemia drug - arsenic trioxide in the presence of eugenol shows differential action on leukemia cells (HL-60) and cardiomyocytes (H9c2) - inference from NMR study.
Toxicol Mech Methods
July 2021
The increased concern of cardiovascular dysfunction by cancer therapeutics has led to more effective treatment strategies. Arsenic trioxide (AsO) is a potential chemotherapeutic agent for acute promyelocytic leukemia (APL), but the effectiveness is affected by potential cardiotoxicity. Researchers have been trying to find out novel modalities to manage the adverse effects of AsO.
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