Dietary manganese nano-particles improves gene regulation and biochemical attributes for mitigation of lead and ammonia toxicity in fish.

In the present study, we explored the capability of manganese nanoparticles (Mn-NPs) to alleviate the toxicity induced by lead (Pb) and ammonia (NH) toxicity in Oreochromis niloticus (GIFT strain). The experiment followed a completely randomized design, including a control group (Mn-NPs-0 mg kg diet) and groups exposed to Pb and NH alongwith Mn-NPs at 2 and 3 mg kg. Cortisol levels were significantly elevated in Pb + NH group whereas reduced by Mn-NPs diets.