Publications by authors named "Reshma Priyanka Danam"

Article Synopsis
  • Oral submucous fibrosis (OSMF) is a chronic condition often caused by areca nut chewing, and this study focuses on how serum trace elements (copper, iron, zinc, selenium) affect its progression and potential for cancer.
  • The research involved 80 participants categorized into four groups based on their areca nut usage and OSMF status, with blood samples taken to analyze trace element levels.
  • Results showed significant increases in serum copper and zinc in individuals with malignant-transformed OSMF compared to healthy controls, suggesting elevated copper may be a key marker for diagnosing OSMF's malignant transformation, warranting further investigation into copper chelation as a treatment option.
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Background: Oral lichen planus (OLP) is a chronic mucocutaneous disease affecting the general population, with its exact etiology remaining unknown. This condition is characterized by T-cell mediated autoimmunity wherein auto-cytotoxic CD8+ T cells precipitate basal cell apoptosis in the oral epithelium. Conventionally, corticosteroids have been the mainstay of treatment for OLP, necessitating the exploration of alternatives to mitigate long-term corticosteroid-related adverse effects.

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Comminuted mandibular fractures are common following a high-velocity injury to the face and jaws. The inherent nature of injury and damage to the underlying hard and soft tissues often complicate the management of comminuted fractures. Traditionally, comminuted fractures were managed by closed reduction and external skeletal fixation.

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Trismus is the most common sequelae of various pathological processes leading to compromised nutritional state in addition to physical and psychological disabilities. Therapeutic interventions are available to relieve trismus, which range from oral usage of pharmacological agents to intralesional steroid therapy. Intraoral appliance therapy can be employed as an alternative or adjuvant treatment for radiotherapy-induced fibrosis and autoimmune disorders such as scleroderma, psychogenic trismus, and oral submucous fibrosis, decreasing the adverse effects associated with other pharmacological interventions.

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