The Association of Norepinephrine Utilization With Mortality Risk in Trauma Patients.

Introduction: While the pillars of trauma resuscitation are surgical hemostasis and blood product administration, norepinephrine (NE) can be used as an adjunct. The goal of this study was to evaluate the relationship between the maximum dose of NE, timing of NE administration, and mortality in trauma patients.

Methods: Patients admitted between January 2013 and January 2021 treated with NE were reviewed.

Hitting the Vasopressor Ceiling: Finding Norepinephrine Associated Mortality in the Critically Ill.

Background: There is no consensus on what dose of norepinephrine corresponds with futility. The purpose of this study was to investigate the maximum infusion and cumulative doses of norepinephrine associated with survival for patients in medical and surgical intensive care units (MICU and SICU).

Materials And Methods: A retrospective review was conducted of 661 critically ill patients admitted to a large academic medical center who received norepinephrine.