Gastrointestinal neuroendocrine tumor with discordant metastatic disease on 111In-pentetreotide SPECT/CT, 18F-DOPA PET/CT and 68Ga-HA-DOTATATE PET/CT.

A 62-year-old man with resected, pathology-proven small bowel neuroendocrine tumor underwent 111In-pentetreotide SPECT/CT, 18F-DOPA PET/CT and 68Ga-HA-DOTATATE PET/CT to assess metastatic disease. The 111In-pentetreotide SPECT/CT scan showed no metastatic disease. Both 18F-DOPA and 68Ga-HA-DOTATATE PET/CT showed hepatic and peritoneal metastatic disease.

Tips for improving consistency of thyroid nodule interpretation with ACR TI-RADS.

Thyroid nodules are very common in the general population. Most are benign and even those that are malignant are typically slow-growing and do not require treatment. Overdiagnosis and overtreatment of thyroid nodules has resulted in significant healthcare costs.

Effect of training on resident inter-reader agreement with American College of Radiology Thyroid Imaging Reporting and Data System.

Background: The American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS) was introduced to standardize the ultrasound characterization of thyroid nodules. Studies have shown that ACR-TIRADS reduces unnecessary biopsies and improves consistency of imaging recommendations. Despite its widespread adoption, there are few studies to date assessing the inter-reader agreement amongst radiology trainees with limited ultrasound experience.

Most common infant health concerns in osteopathic practices in Germany. A survey.

Background: In Germany, more parents have been seeking help from osteopaths for their infants and children in recent years. This implies an increasing demand of reliable evidence regarding the effectiveness of osteopathic intervention for this group.

Objective: To identify the 'typical' (most common) health concerns of parents when presenting their infants (age 0-12 months) in pediatric osteopathic practices.

Osteopathic Treatment of Infants in Their First Year of Life: A Prospective Multicenter Observational Study (OSTINF Study).

Introduction: In Germany in recent years, a growing number of parents are seeking help from osteopaths for the perceived health complaints of their infants and children. However, reliable evidence for the effectiveness of osteopathic interventions for this group of patients is largely lacking.

Objective: To observe and document changes in the symptoms of certain health disturbances, as perceived by parents, during the course of an osteopathic treatment of their baby, and associated side effects.

A New High-Throughput Screening Method to Detect Antimicrobial Volatiles from Metagenomic Clone Libraries.

The ever-growing spread of resistance in medicine and agriculture highlights the need to identify new antimicrobials. Microbial volatile organic compounds (VOCs) are one of the most promising groups of chemicals to meet this need. These rarely exploited molecules exhibit antimicrobial activity and their high vapour pressure makes them ideal for application in surface sterilisation, and in particular, in biofumigation.

Osteopathic treatment of patients with shoulder pain. A pragmatic randomized controlled trial.

Background: Shoulder complaints are common in the general population. Typically, the diagnosis of a specific pathology is lacking. The objective of this trial was to evaluate the effectiveness of an osteopathic treatment in patients suffering from shoulder pain.

Examining Associations Between Strangulation and Depressive Symptoms in Women With Intimate Partner Violence Histories.

Intimate partner violence (IPV) is associated with poor mental health outcomes among women. Studies on IPV and mental health show that experiencing more than one type of IPV often enhances women's depression or depressive symptoms. However, most of these studies conceptualize IPV as physical, psychological, or sexual violence.

Long-Term Course of Shoulders After Ultrasound Therapy for Calcific Tendinitis: Results of the 10-Year Follow-Up of a Randomized Controlled Trial.

Objective: The aim of the study was to follow both the structure- and function-related long-term course of shoulders that had been treated with therapeutic ultrasound for symptomatic calcific tendinitis.

Design: This is a long-term follow-up of 45 shoulders (37 patients) that had been treated for symptomatic calcific tendinitis with either a series of ultrasound or sham ultrasound 10 yrs ago. The main outcome variables were presence of calcium deposits and subacromial impingement on standardized x-ray imaging, shoulder symptoms (Binder score), and function (Constant score).

Direct Characterization of Ultrafast Energy-Time Entangled Photon Pairs.

Energy-time entangled photons are critical in many quantum optical phenomena and have emerged as important elements in quantum information protocols. Entanglement in this degree of freedom often manifests itself on ultrafast time scales, making it very difficult to detect, whether one employs direct or interferometric techniques, as photon-counting detectors have insufficient time resolution. Here, we implement ultrafast photon counters based on nonlinear interactions and strong femtosecond laser pulses to probe energy-time entanglement in this important regime.

Quantum-coherent mixtures of causal relations.

Understanding the causal influences that hold among parts of a system is critical both to explaining that system's natural behaviour and to controlling it through targeted interventions. In a quantum world, understanding causal relations is equally important, but the set of possibilities is far richer. The two basic ways in which a pair of time-ordered quantum systems may be causally related are by a cause-effect mechanism or by a common-cause acting on both.

Observation of Genuine Three-Photon Interference.

Multiparticle quantum interference is critical for our understanding and exploitation of quantum information, and for fundamental tests of quantum mechanics. A remarkable example of multi-partite correlations is exhibited by the Greenberger-Horne-Zeilinger (GHZ) state. In a GHZ state, three particles are correlated while no pairwise correlation is found.

Spectrally Engineering Photonic Entanglement with a Time Lens.

A time lens, which can be used to reshape the spectral and temporal properties of light, requires the ultrafast manipulation of optical signals and presents a significant challenge for single-photon application. In this work, we construct a time lens based on dispersion and sum-frequency generation to spectrally engineer single photons from an entangled pair. The strong frequency anticorrelations between photons produced from spontaneous parametric down-conversion are converted to positive correlations after the time lens, consistent with a negative-magnification system.

Predictors of an unfavorable outcome 1.5 and 12 years after a first, uncomplicated lumbar disc surgery.

Purpose: To identify predictors of both intermediate and long-term unfavorable outcomes after first time, uncomplicated lumbar disc surgery.

Methods: Patients (n = 120) who had undergone lumbar disc surgery were followed up 1.5 and 12 years thereafter.

Phonon-Mediated Nonclassical Interference in Diamond.

Quantum interference of single photons is a fundamental aspect of many photonic quantum processing and communication protocols. Interference requires that the multiple pathways through an interferometer be temporally indistinguishable to within the coherence time of the photon. In this Letter, we use a diamond quantum memory to demonstrate interference between quantum pathways, initially temporally separated by many multiples of the optical coherence time.

An experimental test of noncontextuality without unphysical idealizations.

To make precise the sense in which nature fails to respect classical physics, one requires a formal notion of classicality. Ideally, such a notion should be defined operationally, so that it can be subject to direct experimental test, and it should be applicable in a wide variety of experimental scenarios so that it can cover the breadth of phenomena thought to defy classical understanding. Bell's notion of local causality fulfils the first criterion but not the second.

Degeneration and Instability and the Relation to Patients' Function Late After Lumbar Disc Surgery: Data from a 12-Year Follow-Up.

Objective: To investigate the excess risk of degeneration and segmental instability in operated segments late after lumbar disc surgery in patients with presurgically stable segments, and whether local pathological findings relate to patients' back health.

Design: This retrospective analysis reports on 69 patients 12 years after first-time, uncomplicated lumbar disc surgery. Two independent radiologists evaluated the patients' lumbar functional x-rays; the Back Pain Rating Score (LBP-RS) assessed back-specific function.

Frequency and bandwidth conversion of single photons in a room-temperature diamond quantum memory.

The spectral manipulation of photons is essential for linking components in a quantum network. Large frequency shifts are needed for conversion between optical and telecommunication frequencies, while smaller shifts are useful for frequency-multiplexing quantum systems, in the same way that wavelength division multiplexing is used in classical communications. Here we demonstrate frequency and bandwidth conversion of single photons in a room-temperature diamond quantum memory.

Experimental nonlocal and surreal Bohmian trajectories.

Weak measurement allows one to empirically determine a set of average trajectories for an ensemble of quantum particles. However, when two particles are entangled, the trajectories of the first particle can depend nonlocally on the position of the second particle. Moreover, the theory describing these trajectories, called Bohmian mechanics, predicts trajectories that were at first deemed "surreal" when the second particle is used to probe the position of the first particle.

Certifying the Presence of a Photonic Qubit by Splitting It in Two.

We present an implementation of photonic qubit precertification that performs the delicate task of detecting the presence of a flying photon without destroying its qubit state, allowing loss-sensitive quantum cryptography and tests of nonlocality even over long distance. By splitting an incoming single photon in two via parametric down-conversion, we herald the photon's arrival from an independent photon source while preserving its quantum information with up to (92.3±0.

Development of an Innovative Treatment Paradigm for Intimate Partner Violence Victims With Depression and Pain Using Community-Based Participatory Research.

Intimate partner violence (IPV) is a public health issue with complex physical health, mental health and social consequences that can exacerbate survivors' barriers to health care engagement and support. Furthermore, health care professionals are often unaware of or feel ill-equipped to address survivors' complex needs. Depression and chronic pain are particularly prevalent co-occurring problems for survivors and can impede engagement and outcomes in traditional health care.

Narrative Exposure Therapy: A Proposed Model to Address Intimate Partner Violence-Related PTSD in Parenting and Pregnant Adolescents.

Pregnant and parenting adolescents experience high rates of intimate partner violence (IPV) and its sequelae posttraumatic stress disorder (PTSD) and depression. Narrative exposure therapy (NET) is an innovative intervention that has demonstrated strong preliminary evidence in improving mental health. The specific aims of this article are 3-fold: (1) provide a brief background about IPV-related PTSD and depression among pregnant and parenting adolescents; (2) describe NET's theoretical principles, its therapeutic process, and provide a review of existing evidence; and (3) discuss NET as a potential treatment to address the mental health burden among adolescents experiencing IPV-related PTSD and depression.

NF-κB-repressing factor phosphorylation regulates transcription elongation via its interactions with 5'→3' exoribonuclease 2 and negative elongation factor.

NF-κB-repressing factor (NKRF) inhibits transcription elongation by binding to specific sequences in target promoters. Stimuli such as IL-1 have been shown to overcome this inhibitory action and enable the resumption of transcription elongation machinery by an unknown mechanism. Using mass spectrometry and in vitro phosphorylation analyses, we demonstrate that NKRF is phosphorylated within 3 different domains in unstimulated HeLa cells.