Publications by authors named "Renxiang Tang"

Article Synopsis
  • A new extension to the 'Cobiveco' biventricular coordinate system has been introduced to improve anatomical registration of heart ventricles by including complex regions like outflow tracts and valve annuli.
  • The proposed CobivecoX system employs a unique algorithm to identify intervalvular bridges and assign specific coordinates for precise local positioning in these areas.
  • Validation of this method was conducted using curated three-dimensional models from cardiac MRI, ensuring that universal cardiac coordinates can be effectively applied to diverse ventricular shapes relevant to both normal hearts and those with congenital conditions.
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Article Synopsis
  • Abdominal aortic aneurysms (AAAs) are dangerous due to their risk of rupture and complications from treatment, leading to interest in less invasive therapies to manage them.
  • This study tested the effects of pentagalloyl glucose (PGG) on two experimental mouse models with induced aortic injuries, using ultrasound imaging and tissue analysis to assess outcomes.
  • Results showed that while PGG treatment did not alter the maximum aortic diameter, it did significantly decrease calcium deposits and improve certain strain measurements, indicating its potential benefits in managing arterial health.
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In this article, we demonstrate a wireless and passive physiological pressure sensing scheme that utilizes ultrasound imaging of an implantable microfluidic based pressure sensitive transducer. The transducer consists of a sub-mm scale pressure sensitive membrane that covers a reservoir filled with water and is connected to a hydrophobic micro-channel. Applied pressure onto the transducer deflects the membrane and pushes the water from the reservoir into the channel; the water's travelling distance in the channel is a function of the applied pressure, which is quantitatively measured by using a 40 MHz ultrasound imaging system.

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Targeted therapy is not yet approved for esophageal cancer (EC). In this study, we first evaluated EGFR gene and protein expression in 70 Chinese EC patient tumor samples collected during surgery. We then established 23 patient-derived EC xenograft (PDECX) models and assessed the efficacy of theliatinib, a potent and highly selective EGFR inhibitor currently in Phase I clinical study, in 9 PDECX models exhibiting various EGFR expression levels.

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