FeO/Ni nanoparticles anchored nitrogen-doped porous carbon derived from core-shell MOF for simultaneous electrochemical detection of dopamine and 5-hydroxytryptamine.

Pre-designed core-shell metal-organic frameworks (MOFs@MOFs) with customized functionalities can enhance the material properties compared to conventional single MOFs. The porous carbon composites derived from MOFs@MOFs also have excellent functionality due to the presence of multiple metal/metal oxide nanoparticles. This paper synthesized a novel MOFs@MOFs composite (MIL-101(Fe)@Ni-MOF) with a core-shell structure with MIL-101(Fe) as the core and Ni-MOF as the shell.

Sulforaphane alleviates psoriasis by enhancing antioxidant defense through KEAP1-NRF2 Pathway activation and attenuating inflammatory signaling.

Psoriasis is a chronic inflammatory skin disease that affects millions of people worldwide. Sulforaphane (SFN) has been shown to have anti-inflammatory and antioxidant properties. In this study, we investigated the effects of SFN on a mouse model of psoriasis induced by imiquimod (IMQ) and its underlying molecular mechanism.

Vitamin D attenuates DNCB-induced atopic dermatitis-like skin lesions by inhibiting immune response and restoring skin barrier function.

Atopic dermatitis (AD) is a common chronic inflammatory skin disease causing erythema and itching. The etiology of AD is complex and not yet clear. Vitamin D is a fat-soluble vitamin that promotes skin cell growth and differentiation and regulates immune function.

Creatine modulates cellular energy metabolism and protects against cancer cachexia-associated muscle wasting.

Cancer cachexia is a multifactorial syndrome defined by progressive loss of body weight with specific depletion of skeletal muscle and adipose tissue. Since there are no FDA-approved drugs that are available, nutritional intervention is recommended as a supporting therapy. Creatine supplementation has an ergogenic effect in various types of sports training, but the regulatory effects of creatine supplementation in cancer cachexia remain unknown.

Targeting HSP90 Inhibits Proliferation and Induces Apoptosis Through AKT1/ERK Pathway in Lung Cancer.

Lung cancer is one of the most common malignant cancers worldwide. Searching for specific cancer targets and developing efficient therapies with lower toxicity is urgently needed. HPS90 is a key chaperon protein that has multiple client proteins involved in the development of cancer.

NaVO/Activated Carbon Hybrid Cathode for High-Performance Lithium-Ion Capacitors.

Lithium-ion hybrid capacitors (LICs) are regarded as one of the most promising next generation energy storage devices. Commercial activated carbon materials with low cost and excellent cycling stability are widely used as cathode materials for LICs, however, their low energy density remains a significant challenge for the practical applications of LICs. Herein, NaVO nanobelts (NaVO) were prepared and combined with commercial activated carbon YP50D to form hybrid cathode materials.