Isoorientin protects lipopolysaccharide-induced acute lung injury in mice via modulating Keap1/Nrf2-HO-1 and NLRP3 inflammasome pathways.

Acute lung injury (ALI) is a pulmonary disease with high mortality. The present study investigated the protective effect of isoorientin (ISO) on lipopolysaccharide (LPS)-induced ALI compared with Thalictrum minus L. (TML).

Thalictrum minus L. ameliorates particulate matter-induced acute lung injury in mice.

Ethnopharmacological Relevance: Thalictrum minus L., which is widespread across Eurasia, is utilized as a folk medicine for treating dysentery, bedsore, fungal infection and lung inflammation in China, Mongolia and Iran.

Aim Of The Study: A Mongolian folk medicinal plant named Thalictrum minus L.

The protective effects of Thalictrum minus L. on lipopolysaccharide-induced acute lung injury.

Ethnopharmacological Relevance: Thalictrum minus L., a Mongolian folk medicinal plant, was applied for the treatment of bacterial and fungal infection, tuberculosis and lung inflammation.

Aim Of The Study: The present work aims to elucidate the protective effects of Thalictrum minus L.