Publications by authors named "Rensson H Celiz"
Article Synopsis
- Taenia solium causes neurocysticercosis (NCC), leading to complications like hippocampal atrophy and adult-onset epilepsy, particularly in developing regions.* -
- Researchers examined brain tissue from rats infected with T. solium, analyzing gene expression related to inflammation and healing after 4 months.* -
- Findings showed overexpression of inflammatory cytokines near the parasite and in distant areas, suggesting that these molecular pathways could link NCC to hippocampal atrophy.*
Neurocysticercosis (NCC) is a helminth infection affecting the central nervous system caused by the larval stage (cysticercus) of Taenia solium. Since vascular alteration and blood-brain barrier (BBB) disruption contribute to NCC pathology, it is postulated that angiogenesis could contribute to the pathology of this disease. This study used a rat model for NCC and evaluated the expression of two angiogenic factors called vascular endothelial growth factor (VEGF-A) and fibroblast growth factor (FGF2).
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