Low vaccination and infection rate of Omicron in patients with inflammatory bowel disease: a comparative study of three unique cohorts.

Background: The SARS-CoV-2 Omicron variant caused a large-scale outbreak of COVID-19 in Shanghai, China. Patients with inflammatory bowel disease (IBD) are at high risk of infection due to immunosuppressive interventions. We aimed to investigate the vaccination information of patients with IBD and update a vaccination guide based on a comparison of vaccination in asymptomatic carriers and healthy individuals.

Construction and Validation of a risk model Based on Cuprotosis-related LncRNAsin Colon Adenocarcinoma.

Cancer cells are significantly impacted by copper-induced cell death (cuprotosis). Long noncoding RNAs (lncRNAs) are crucial in the developmental process of colon adenocarcinoma  (COAD). The ability of Cuprotosis-related lncRNA biomarkers to predict COAD prognosis, on the other hand, remains uncertain.