Lipidomic profiling of bile in distinguishing benign from malignant biliary strictures: a single-blinded pilot study.

Objectives: Ascertaining the benign or malignant nature of biliary strictures may be challenging. Oxidized phospholipids (oxPLs) play an important role in tumor apoptosis and may be elevated in malignant biliary strictures. The objective of the study was to investigate whether oxPLs are enriched in the bile of malignant biliary strictures.