Impact of the 2023 FIGO Staging System for Endometrial Cancer on the Use of Imaging Services: An Indian Perspective.

The new 2023 update of the International Federation of Gynecology and Obstetrics (FIGO) staging system for endometrial cancer incorporates the advances made in the understanding of the pathology and molecular classifications into the staging system. While the new staging system aids in precision medicine and may lead to better documentation of prognostic risk categories of endometrial cancer, it is complex and calls for an integrated approach and better communication between multiple disciplines involved in the management of endometrial cancer. In this review article, we address how the referral patterns to imaging services might change considering the updated staging system for endometrial cancer.

Protonated CN Nanosheets for Enhanced Energy Storage in Symmetric Supercapacitors through Hydrochloric Acid Treatment.

Next-generation electrochemical energy storage materials are essential in delivering high power for long periods of time. Double-layer carbonaceous materials provide high power density with low energy density due to surface-controlled adsorption. This limitation can be overcome by developing a low-cost, more abundant material that delivers high energy and power density.

Scoring system for predicting ovarian necrosis in adnexal torsion using an ultra-short optimized MRI protocol.

Purpose: To evaluate a MRI scoring system predicting haemorrhagic necrosis in adnexal torsion with intraoperative and/or histopathological correlation using an abbreviated and optimized MRI protocol.

Methods: This retrospective observational study includes patients with adnexal torsion who underwent Magnetic Resonance Imaging(MRI) and surgery. T2 sequences were evaluated by three observers of varying experience for following findings: Hypo-intensity of ovarian stroma, around the follicle, cyst wall or ovarian capsule and the twisted pedicle.

Radiological Spectrum of Pseudoangiomatous Stromal Hyperplasia of Breast-A Case Series.

Pseudoangiomatous stromal hyperplasia (PASH) is a benign mesenchymal tumor-like lesion of the breast. It is commonly seen as incidental background changes of the intralobular stroma in biopsy specimens performed for other breast lesions. Less frequently, it presents as a nodular form that has a benign morphology on imaging, mimicking fibroadenoma or as a diffuse form causing progressive massive gigantomastia.

Deciphering functional characteristics and in-vitro bioactive properties of banana central core stem powder.

Banana central core stem powder (CCSP) of seven varieties were studied to elucidate their functional, therapeutic properties and bioactiveprofiling.CCSP recorded whiteness index in the range of 75.80-80.

Pyridine coupled pyrazole analogues as lethal weapon against MRSA: An in-vitro and in-silico approach.

The treatment of Methicillin-resistant staphylococcus aureus (MRSA) infections has become challenging due to the growth of multidrug resistance in the bacteria. Here we report the synthesis of pyridine-coupled pyrazoles as an antimicrobial agent against MRSA. A series of pyridine coupled pyrazoles were synthesized and synthesized compounds were characterized using FT-IR, H NMR, and Mass spectroscopy.

Comparison of T2 relaxometry and PET CT in the evaluation of patients with mesial temporal lobe epilepsy using video EEG as the reference standard.

Purpose: Our study aimed to compare the sensitivity of T2 relaxometry and positron emission tomography - computed tomography (PET/CT) in patients with a history suggestive of mesial temporal lobe epilepsy using video electroencephalography (EEG) as the reference standard.

Material And Methods: In our study, 35 patients with a history suggestive of mesial temporal lobe epilepsy were subjected to conventional magnetic resonance imaging (MRI), T2 relaxometry, and PET/CT. The results of each of the studies were compared with video EEG findings.

Does dual-energy abdominal computed tomography increase the radiation dose to patients: a prospective observational study.

Purpose: The aim of our study was to compare single-energy (SECT) and dual-energy (DECT) abdominal computed tomography (CT) examinations in matched patient cohorts regarding the differences in effective radiation dose (ERD) and image quality performed in a third-generation dual-source computed tomography (DSCT) scanner.

Material And Methods: Our study included 100 patients, who were divided randomly into 2 groups. The patients included in Group A were scanned by SECT, and Group B members were scanned by DECT.

Estimation of Accuracy of B-Mode Sonography and Elastography in Differentiation of Benign and Malignant Lymph Nodes With Cytology as Reference Standard: A Prospective Study.

Purpose:  To prospectively estimate the reliability of B-mode ultrasonography and sonoelastography in differentiating benign and malignant cervical lymph nodes with cytological findings as to the reference standard.

Materials And Methods: A total of 50 patients referred for sonography for enlarged cervical lymph nodes were included in the study. They were subjected initially to B-mode ultrasonography and sonoelastography and later underwent fine-needle aspiration cytology (FNAC) in the same sitting.

Renal Lymphangiectasia: An Unusual Mimicker of Cystic Renal Disease - A Case Series and Literature Review.

Cystic renal lesions are commonly seen on a daily basis in abdominal imaging. Even though most cystic renal lesions are benign simple cysts, complex and multifocal cystic renal diseases are also common with a vast number of differentials. One of the rare mimickers of this condition is renal lymphangiectasia, and the disease can be diagnosed if radiologists are aware of the imaging findings, and this can help the physician to offer the appropriate treatment.

Impact of tunable 2-(1-indol-3-yl)acetonitrile based fluorophores towards optical, thermal and electroluminescence properties.

Herein, we have synthesized 4,5-diphenyl-1-imidazole and 2-(1-indol-3-yl)acetonitrile based donor-π-acceptor fluorophores and studied their optical, thermal, electroluminescence properties. Both the fluorophores exhibit high fluorescence quantum yield ( = <0.6) and good thermal stability ( = <300 °C), and could be excellent candidates for OLED applications.

Spectroscopic investigation and computational studies on the interaction of Acriflavine with various estrogens.

The fluorescence quenching of Acriflavine (AFN) by certain estrogens was examined in aqueous media by employing steady state and time-resolved fluorescence measurements. The absorption spectra of AFN change with significant bathochromic shift in presence of quencher molecules. The quenching behavior was examined by correlating the bimolecular quenching rate constant (k) with the free energy change (ΔG).

Influence of Different Zeolite Frameworks on the Geometry of Platinum(II)tetraammine Complex.

The structural changes in the guest platinum(II)tetraammine complex due to the steric and electronic interactions with the host zeolite frameworks LTL, MWW, and Y have been investigated using density functional theory calculations. It is observed that the square planar geometry of platinum(II)tetraammine complex has been distorted to nonplanar geometry when encapsulated in supercages of zeolite framework. The distortion is found to be higher in LTL than that in Y and MWW frameworks, without affecting the nature of the zeolite framework.

Novel Bioactive Co(II), Cu(II), Ni(II) and Zn(II) Complexes with Schiff Base Ligand Derived from Histidine and 1,3-Indandione: Synthesis, Structural Elucidation, Biological Investigation and Docking Analysis.

Novel bioactive complexes of Co(II), Cu(II), Ni(II) and Zn(II) metal ions with Schiff base ligand derived from histidine and 1,3-indandione were synthesized and thoroughly characterized by various analytical and spectral techniques. The biological investigations were carried out to examine the efficiency of the binding interaction of all the complexes with calf thymus DNA (CT-DNA). The binding properties were studied and evaluated quantitatively by K and K values using UV-visible, fluorescence spectroscopy and voltammetric techniques.

A review of principles in design and usability testing of tactile technology for individuals with visual impairments.

To lay the groundwork for devising, improving, and implementing new technologies to meet the needs of individuals with visual impairments, a systematic literature review was conducted to: a) describe hardware platforms used in assistive devices, b) identify their various applications, and c) summarize practices in user testing conducted with these devices. A search in relevant EBSCO databases for articles published between 1980 and 2014 with terminology related to visual impairment, technology, and tactile sensory adaptation yielded 62 articles that met the inclusion criteria for final review. It was found that while earlier hardware development focused on pin matrices, the emphasis then shifted toward force feedback haptics and accessible touch screens.

Central and peripheral nervous system involvement in neuromelioidosis.

We report a case of a 33-year-old Sri Lankan man who presented with flaccid quadriparesis with brainstem signs and acute motor axonal polyneuropathy. MRI of the brain showed multiple abscesses with ring enhancement seen predominantly in the brainstem and upper cervical cord. The patient was initially treated with intravenous immunoglobulin, considering this to be a form of Guillain-Barré syndrome.

Synthesis, characterization and binding interactions of amino acids coupled perylene diimides with colloidal doped and undoped TiO₂.

Two sensitizers based on amino acids coupled with perylene moiety having absorption in the visible region have been designed and their interaction with doped and undoped TiO2 for the application of dye sensitized solar cells (DSSCs) has been studied. The synthesized compounds PDI-PA and PDI-AA were characterized using (1)H and (13)C NMR, Mass and FT-IR spectroscopic techniques. The optical properties and lifetime measurements of the sensitizers were analyzed using various solvents with different polarity.

Antibacterial potential of rutin conjugated with thioglycolic acid capped cadmium telluride quantum dots (TGA-CdTe QDs).

Quantum dots not only act as nanocarrier but also act as stable and resistant natural fluorescent bio markers used in various in vitro and in vivo photolabelling and biological applications. In this study, the antimicrobial potential of TGA-CdTe QDs and commercial phenolics (rutin and caffeine) were investigated against Escherichiacoli. UV absorbance and fluorescence quenching study of TGA-CdTe QDs with rutin and caffeine complex was measured by spectroscopic technique.

Investigation on the inclusion and toxicity of acriflavine with cyclodextrins: a spectroscopic approach.

Acriflavine hydrochloride (AFN) is a prospective drug worn in the eradication of HIV1 infection. The toxicity and adverse side effects renders the potent drug to limits its usage. However, to overcome the dilemma we have aimed to select carriers with great complexation efficiencies in different cyclodextrins (CDs) of varying cavity size.

"Turn-on-off-on" fluorescence switching of quantum dots-cationic porphyrin nanohybrid: a sensor for DNA.

In this article, we describe a new platform for probing double stranded DNA (dsDNA) by tracing the "on-off-on" fluorescence signals of quantum dots-cationic porphyrin utilizing fluorescence and synchronous fluorescence measurements. Electrostatic interaction between the negatively charged thioglycolic acid capped CdTe quantum dots (CdTe-TGA QDs) and positively charged porphyrin surfaces leads to drastic quenching (turning off) of the donor by an effective electron transfer process. Interestingly, after the addition of calf thymus DNA (CtDNA), the porphyrins peel off from the quantum dot surface and bind to dsDNA, resulting in the restoration of fluorescence intensity of quantum dots (turning on).

Highly emissive luminogens based on imidazo[1,2-a]pyridine for electroluminescent applications.

A search for novel organic luminogens led us to design and synthesize some N-fused imidazole derivatives based on imidazo[1,2-a]pyridine as the core and arylamine and imidazole as the peripheral groups. The fluorophores were synthesized through a multicomponent cascade reaction (A(3) coupling) of a heterocyclic azine with an aldehyde and alkyne, followed by Suzuki coupling and a multicomponent cyclization reaction. All of the compounds exhibited interesting photophysical responses, especially arylamine-containing derivatives, which displayed strong positive solvatochromism in the emission spectra that indicated a more polar excited state owing to an efficient charge migration from the donor arylamine to the imidazo[1,2-a]pyridine acceptor.

Bioimaging, antibacterial and antifungal properties of imidazole-pyridine fluorophores: synthesis, characterization and solvatochromism.

A series of imidazole derivatives connected with pyridine moiety through phenyl groups were synthesized by using Suzuki coupling followed by multicomponent cyclization reaction. Results obtained from spectroscopic ((1)H NMR, (13)C NMR, Mass) and single crystal X-ray diffraction analysis of synthesized compound was in very good agreement with its chemical structure. UV-Vis and fluorescence studies in various solvents with different polarity demonstrated that these compounds were sensitive to the polarity of the microenvironment.

Enhancement of anti arthritic effect of quercetin using thioglycolic acid-capped cadmium telluride quantum dots as nanocarrier in adjuvant induced arthritic Wistar rats.

In this present study, we investigated thio glycolic acid-capped cadmium telluride quantum dots (TGA-CdTe QDs) as nano carrier to study the antiarthritic activity of quercetin on adjuvant induced arthritic Wistar rats. The free radical scavenging activity of QDs-QE complex was evaluated by 2,2'-azinobis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS), 2,2-diphenyl-1-picrylhydrazyl (DPPH), nitric oxide (NO) and superoxide anion scavenging assays. Fifteen days after adjuvant induction, arthritic rats received QDs-QE complex orally at the dose of 0.