To quantify the number and type of new opioid-related continuing pharmacy education (CPE) activities offered by continuing education divisions (CEDs) at US schools and colleges of pharmacy from 2015 through 2018, and to determine the number of pharmacists who completed opioid-related CPE activities. Data was derived from the database of CPE activities maintained by the Accreditation Council for Pharmacy Education (ACPE), which is the sole accreditation agency for all providers of CPE, including pharmacy schools. Data were filtered to include only pharmacy school CPE providers.
View Article and Find Full Text PDFBackground And Aims: Patients with opioid use disorder (OUD) must be able to obtain prescribed buprenorphine/naloxone films (BUP/NX) and naloxone nasal spray (NNS) from a pharmacy promptly to reduce risk for a recurrence of use and subsequent morbidity and mortality. Telephone audits have identified concerning gaps in availability of NNS within US pharmacies, but the availability of BUP/NX has not been rigorously evaluated. This study estimated the availability of BUP/NX and NNS in the US state of Texas and compared availability by pharmacy type and metropolitan status.
View Article and Find Full Text PDFIntroduction: Maintaining abstinence through the opioid withdrawal period is a substantial barrier to treatment for patients with opioid use disorder. The alpha-2 agonist lofexidine has demonstrated efficacy and safety in clinical trials, but pragmatic studies describing its use in clinical practice are lacking. This case series describes the use of lofexidine for opioid withdrawal symptoms in an inpatient addiction treatment facility.
View Article and Find Full Text PDFBackground And Purpose: Falls are the leading cause of morbidity and mortality among US older adults and result in considerable medical and social consequences. Community-based screenings are a type of intervention that provides accessible fall risk screening and education at no cost to the participants. However, little is known about whether or how participants change behavior after screening events.
View Article and Find Full Text PDFIntroduction: Evidence-based fall prevention (EBFP) programs significantly decrease fall risk, falls, and fall-related injuries in community-dwelling older adults. To date, EBFP programs are only validated for use among people with normal cognition and, therefore, are not evidence-based for adults with intellectual and/or developmental disorders (IDD) such as Alzheimer's disease and related dementias, cerebral vascular accident, or traumatic brain injury.
Background: Adults with IDD experience not only a higher rate of falls than their community-dwelling, cognitively intact peers but also higher rates and earlier onset of chronic diseases, also known to increase fall risk.
Three-dimensional (3D) images of flame emission are reported using a single direction of optical access. A Cassegrain system was designed with narrow depth of field. Images from this system are dominated by emission from the focused object plane with defocused contributions from out-of-plane structures.
View Article and Find Full Text PDFBackground: Unintentional falls is an increasing public health problem as incidence of falls rises and the population ages. The Centers for Disease Control and Prevention reports that 1 in 3 adults aged 65 years and older will experience a fall this year; 20% to 30% of those who fall will sustain a moderate to severe injury. Physical therapists caring for older adults are usually engaged with these patients after the first injury fall and may have little opportunity to abate fall risk before the injuries occur.
View Article and Find Full Text PDFA diode laser sensor was developed for partial pressure and temperature measurements using a single water vapor transition. The Lorentzian half-width and line intensity of the transition were calibrated for conditions relevant to proton exchange membrane (PEM) fuel cell operation. Comparison of measured and simulated harmonics from wavelength-modulation spectroscopy is shown to yield accuracy of +/-2.
View Article and Find Full Text PDFTwo-line laser-induced-fluorescence (LIF) thermometry is commonly employed to generate instantaneous planar maps of temperature in unsteady flames. The use of line scanning to extract the ratio of integrated intensities is less common because it precludes instantaneous measurements. Recent advances in the energy output of high-speed, ultraviolet, optical parameter oscillators have made possible the rapid scanning of molecular rovibrational transitions and, hence, the potential to extract information on gas-phase temperatures.
View Article and Find Full Text PDFQuantitative hydroxyl concentration time-series measurements have been obtained by picosecond time-resolved laser-induced fluorescence in a series of methane-air and hydrogen-argon-air nonpremixed flames. The recovery of a quantitative time series is complicated by the need to account for fluctuations in the fluorescence lifetime. We have recently developed instrumentation that enables the simultaneous measurement of fluorescence signal and lifetime.
View Article and Find Full Text PDFWe report on a novel laser-induced fluorescence triple-integration method (LIFTIME) that is capable of making rapid, continuous fluorescence lifetime measurements by a unique photon-counting technique. The LIFTIME has been convolved with picosecond time-resolved laser-induced fluorescence, which employs a high-repetition-rate mode-locked laser, permitting the eventual monitoring of instantaneous species concentrations in turbulent flames. We verify the technique by application of the LIFTIME to two known fluorescence media, diphenyloxazole (PPO) and quinine sulfate monohydrate (QSM).
View Article and Find Full Text PDFQuantitative two-point hydroxyl time-series measurements have been performed in a turbulent nonpremixed flame by using two-point picosecond time-resolved laser-induced fluorescence. The current diagnostic system has been improved from its preliminary version to address optical aberrations and fluorescence lifetime fluctuations. In particular, with a newly designed collection system, the aberration-limited blur spot is reduced from 6 mm to 180 microm.
View Article and Find Full Text PDFSpine (Phila Pa 1976)
January 2006
Study Design: Retrospective single-center consecutive case series with two [corrected] year follow-up.
Objectives: To examine kyphoplasty [corrected] patients for long-lasting clinical and radiological outcomes [corrected] including effects on [corrected] vertebral body shape.
Summary Of Background Data: Kyphoplasty is the minimally-invasive [corrected] reduction and stabilization of vertebral body fractures [corrected] resulting in pain relief and improved physical function as described in our previously published one-year outcomes report [corrected]
Methods: Safety (complications and cement extravasation) was monitored in all 117 patients (151 fractures) treated through December 2001.
We report a technique that is capable of making simultaneous two-point time-series measurements of minor-species concentrations in turbulent flames. The experimental setup, which incorporates picosecond time-resolved laser-induced fluorescence, has a spatial resolution of less than 250 microm and a temporal resolution of less than 100 micros, which spatially and temporally resolve microscales in many turbulent flows. Two-point time-series data are given for a standard turbulent nonpremixed flame at Re= 10,000, including a discussion of potential implications.
View Article and Find Full Text PDFObject: Vertebral body (VB) deformities have been associated with increased patient morbidity and mortality rates. The aim of this retrospective, consecutive single-center cohort study was to determine the effectiveness of kyphoplasty in reducing morphometrically defined VB deformity, including deformity shape types (wedge, biconcave, or crush) and grade (severity).
Methods: The authors identified 100 patients (70% women; mean age 76.
Object: The authors assessed the safety of balloon kyphoplasty in the reduction and repair of osteopenic vertebral compression fractures and report functional outcomes (back pain and activity levels) in the first 96 patients (with 133 fractures) at their institution. Additionally they provide radiographic outcomes in the first 26 patients (41 fractures) treated and followed for 1 year.
Methods: The authors conducted a retrospective chart review of functional outcomes and evaluated radiographs obtained at 1 week, 1 month, 3 months, 6 months, and 1 year postoperatively.
We report a developing technique capable of making continuous time-series measurements of naturally occurring minor-species concentrations. The high repetition rate of the mode-locked laser used in this technique allows for the study of transient combustion events, such as turbulence, and their effect on minor-species concentrations. The technique is applied to make CH fluorescence time-series measurements and to calculate power spectral densities in a turbulent nonpremixed flame.
View Article and Find Full Text PDFA case of an anterior third ventricular meningioma in a 17-year-old girl is presented. Gross total resection of this tumor with minimal morbidity was accomplished by transcallosal exposure through a frontal craniotomy. A review of the literature implies that surgical morbidity and mortality for the removal of third ventricular meningiomas markedly improved with the use of the operating microscope.
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