Automatic Segmentation and Classification for Antinuclear Antibody Images Based on Deep Learning.

Antinuclear antibodies (ANAs) testing is the main serological diagnosis screening test for autoimmune diseases. ANAs testing is conducted principally by the indirect immunofluorescence (IIF) on human epithelial cell-substrate (HEp-2) protocol. However, due to its high variability and human subjectivity, there is an insistent need to develop an efficient method for automatic image segmentation and classification.

A hierarchical flower-like hollow alumina supported bimetallic AuPd nanoparticle catalyst for enhanced solvent-free ethylbenzene oxidation.

Currently, oxidation of alkylaromatics is considered as one of the most crucial chemical technologies to produce high added-value alcohols, ketones and carboxylic acids, due to its significant importance both in fine synthetic chemistry and in the academic field. In this work, a novel hierarchical marigold-like hollow alumina supported bimetallic AuPd nanoparticle catalyst was successfully fabricated and employed for highly efficient solvent-free ethylbenzene oxidation to produce acetophenone with the coexistence of both molecular oxygen and tert-butyl hydroperoxide as the oxidant and the initiator. The as-fabricated bimetallic AuPd nanocatalyst conferred a superior catalytic performance to the corresponding monometallic counterparts and commercial Al2O3 or solid Al2O3 microsphere supported AuPd ones, along with a high acetophenone selectivity of 88.

Prenatal Dexamethasone Exposure Increases the Susceptibility to Autoimmunity in Offspring Rats by Epigenetic Programing of Glucocorticoid Receptor.

. Prenatal glucocorticoids (GC) can induce long term effects on offspring health. However, reports and related studies regarding the prolonged effects of prenatal GC on the development of autoimmunity are limited.