Kinetics of a new porcine taste-bud tissue biosensor for the detection of umami substances and their synergistic effect.

Umami substances are nutrients to humans, and their synergistic effect is associated with food acceptance. In this study, a new biosensor was developed to detect umami substances, their synergistic effect, and detection kinetics. Porcine taste-bud tissues were used as the sensing element, and the umami substance signals were characterized using an electrochemical workstation.

A novel deletion variant in TRAPPC2 causes spondyloepiphyseal dysplasia tarda in a five-generation Chinese family.

Background: Spondyloepiphyseal dysplasia tarda (SEDT) is a rare X-linked recessive inherited osteochondrodysplasia caused by mutations in the TRAPPC2 gene. It is clinically characterized by disproportionate short stature and early onset of degenerative osteoarthritis. Clinical diagnosis can be challenging due to the late-onset of the disease and lack of systemic metabolic abnomalites.

In vivo morphological and functional evaluation of the lateral pterygoid muscle: a diffusion tensor imaging study.

Objective:: To explore the feasibility of morphological and functional evaluation of the lateral pterygoid muscle (LPM) by diffusion tensor imaging (DTI) in vivo.

Methods:: 30 healthy volunteers underwent DTI with the jaw in the rest position, opening and clenching. Diffusion parameters of the superior head of the LPM (SHLP) and the inferior head of the LPM (IHLP) at different jaw positions were calculated.

MR imaging of patients with lateral epicondylitis of the elbow: is the common extensor tendon an isolated lesion?

Objective: To investigate whether an injury of the common extensor tendon (CET) is associated with other abnormalities in the elbow joint and find the potential relationships between these imaging features by using a high-resolution magnetic resonance imaging (MRI).

Methods: Twenty-three patients were examined with 3.0 T MR.

MRI manifestations and differentiated diagnosis of postoperative spinal complications.

To analyze MR manifestations of postoperative spinal complications and investigate the value of MRI in the diagnosis and differentiated diagnosis, 114 cases of spinal postoperative complications were analyzed retrospectively and compared with the clinical data. The results showed that the main postoperative spinal complications included spinal stenosis (n=33, consisting of 21 cases of epidural fibrosis and 12 cases of epidural hematoma or epidural abscess), lack of spinal stability (n=43), infection (n=23, consisting of 7 cases of para-spinal soft-tissue infection, 5 cases of vertebral discitis, 4 cases of vertebral and appendix infection, 3 cases of epidural abscess, 2 cases of myelitis, 2 cases of spinal arachnoiditis), others (n=28, consisting of 12 cases of inner fixation failure, 9 cases of epidural hematoma, 7 cases of cerebrospinal fluid gusher). It is concluded that MRI can specifically display all kinds of postoperative spinal complications, and is of significant value in the diagnosis and differentiated diagnosis of postoperative spinal complications.

Functional computed tomographic quantification of angiogenesis in rabbit VX2 soft-tissue tumor before and after interventional therapy.

Objective: Our purpose was to investigate the applicative value of multislice spiral computed tomography (CT) perfusion imaging on quantitative assessment of tumor angiogenesis before and after transcatheter arterial embolization and monitoring the early interventional therapeutic effect in malignant solid tumors.

Methods: Sixteen New Zealand white rabbits successfully implanted VX2 tumor in the unilateral proximal thigh were divided into 2 groups (8 per group) at random and performed conventional CT plain scan and perfusion scan 14 days after implantation and 3 days after interventional therapy, respectively. The values of blood flow (BF), blood volume (BV), mean transit time (MTT), and permeability surface area product (PS) in VX2 tumors and normal muscles were computed after intravenous bolus administration of iodinated contrast medium, and the differences among them were analyzed.

Application of multislice spiral CT for guidance of insertion of thoracic spine pedicle screws: an in vitro study.

To investigate the value of the guidance of three dimensional (3-D) reconstruction of multi-slice spiral CT (MSCT) for the placement of pedicle screws, the 3-D anatomical data of the thoracic pedicles were measured by MSCT in two embalmed human cadaveric thoracic pedicles spines (T1-T10) to guide the insertion of pedicle screws. After pulling the screws out, the pathways were filled with contrast media. The PW, PH, TSA and SSA of developed pathways were measured on the CT images and they were also measured on the real objects by caliper and goniometer.

Experimental study of multi-slice spiral CT perfusion imaging in VX2 soft-tissue tumor of rabbits.

An experimental animal model of malignant soft-tissue tumor was established to investigate the applied value of multi-slice spiral CT perfusion imaging preliminarily. Ten New Zealand white rabbits which were implanted with VX2 tumor in either proximal thigh were subjected to CT plain scan and perfusion scan two weeks later respectively, then the original perfusion images were transmitted to AW4.0 Workstation.

Gadolinium-enhanced MR imaging of epiphyseal and metaphyseal marrow in normal piglets.

The purpose of this study is to define the appearance of normal epiphyseal and metaphyseal marrow and normal changes of marrow due to fatty conversion on Gadolinium (Gd)-enhanced MR Imaging. Unenhanced and enhanced T1-weighted MR imaging were performed in proximal and distal femoral ends of 8 healthy piglets at the ages of 2, 4, 6 and 8 weeks, respectively. The changes with age in signal intensity and enhancement ratio of the epiphyseal and metaphyseal marrow with age were examined.

Epiphyseal and physeal cartilage: normal gadolinium-enhanced MR imaging.

To evaluate the normal appearance of epiphyseal and physeal cartilage on Gadolinium (Gd)-enhanced MR imaging. The appearance and enhancement ratios of 20 proximal and distal femoral epiphyses in 10 normal piglets were analyzed on Gd-enhanced MR images. The correlation of the MR imaging appearance with corresponding histological findings of immature epiphyses was examined.

MRI characteristics and transverse relaxation time measurements in normal growing cartilage.

To determine the characteristics of magnetic resonance (MR) signals of normal growing cartilage and identify the difference in transverse relaxation times between physeal and epiphyseal cartilage in vivo. 24 distal femora of 12 two-week-old piglets were imaged on a 1.5 Tesla GE MR scanner.

Extranodal imaging manifestations of non-Hodgkin's lymphoma.

A series of imaging features of extranodal, multi-systemic involvements in Non-Hodgkin's lymphoma (NHL) were investigated. The clinical data and imaging findings of 16 patients with pathologically proved NHL were retrospectively analyzed. The related literatures were reviewed.