Publications by authors named "Rener Mateus Francisco Duarte"
The Interaction of Apical Periodontitis, Cigarette Smoke, and Alcohol Consumption on Liver Antioxidant Status in Rats.
Int J Mol Sci
November 2024
This study aimed to investigate the impact of alcohol (A), secondhand cigarette smoking (ShS), and their combined effect on liver antioxidant activity and hepatic damage in rats with induced apical periodontitis (AP). Thirty-five female Wistar rats were randomly allocated into five groups (n = 7): (1) control (rats without ShS, alcoholic diet, or AP), (2) control-AP (induced AP only), (3) ShS-AP (ShS exposure and induced AP), (4) A-AP (alcoholic diet and induced AP), and (5) A+ShS-AP (alcoholic diet, ShS exposure, and induced AP). Alcohol was administered through semi-voluntary intake, while ShS exposure involved the daily inhalation of cigarette smoke.
View Article and Find Full Text PDFResveratrol prevents offspring's behavioral impairment associated with immunogenic stress during pregnancy.
Prog Neuropsychopharmacol Biol Psychiatry
November 2024
Evidence suggests that prenatal maternal immunological stress is associated with an increased risk of neurological and psychiatric disorders in the developing offspring. Protecting the embryo during this critical period of neurodevelopment, when the brain is especially vulnerable, is therefore crucial. Polyphenols, with their antioxidant and anti-inflammatory properties, offer promising therapeutic approaches.
View Article and Find Full Text PDFChronic exposure to 2,2'-azobis-2-amidinopropane that induces intestinal damage and oxidative stress in larvae of Drosophila melanogaster.
Environ Toxicol Pharmacol
March 2024
Article Synopsis
- Embryonic development is vulnerable to stressors like oxidative stress, which can disrupt normal growth and viability in organisms.* -
- In a study with Drosophila melanogaster larvae, exposure to a free radical generator (AAPH) during different larval stages led to lower hatching rates and increased oxidative damage, particularly affecting the gut.* -
- Observations showed significant morphological changes and increased cell apoptosis, highlighting the detrimental effects of oxidative stress on animal development.*