The Opportunities and Risks of Large Language Models in Mental Health.

Global rates of mental health concerns are rising, and there is increasing realization that existing models of mental health care will not adequately expand to meet the demand. With the emergence of large language models (LLMs) has come great optimism regarding their promise to create novel, large-scale solutions to support mental health. Despite their nascence, LLMs have already been applied to mental health-related tasks.

The Role of Amaranth, Quinoa, and Millets for the Development of Healthy, Sustainable Food Products-A Review.

The selection of sustainable crops adaptable to the rapidly changing environment, which also cater to the dietary needs of the growing population, is a primary challenge in meeting food security. Grains from ancient crops such as amaranth, quinoa, and millets are positioned to address this challenge and hence have gained dietary predominance among cereals and pseudocereals due to their nutritional value and energy efficiency. From a nutritional perspective, they are recognized for their complete protein, phenolic compounds and flavonoids, prebiotic fibers, and essential micronutrients, including minerals and vitamins.

Beyond the Lab: Empirically Supported Treatments in the Real World.

Laboratory studies of empirically supported treatments (ESTs) for mental health problems achieve much higher rates of clinical improvement than has been observed following treatment in the community. This discrepancy is likely to due to limited reliance on ESTs by therapists outside of academia. Concerns about the generalizability of ESTs to patients in the community, who may have comorbid problems, likely limit rates of adoption.

Physicochemical and Sensory Properties of Cold Pressed Oils from Florida Hamlin and Valencia Oranges Affected by Huanglongbing.

Cold pressed oils from huanglongbing (HLB) symptomatic (SY) and asymptomatic (AS) Hamlin and Valencia oranges were assessed for 2 y (2014 to 2015 and 2015 to 2016 seasons) with 2 harvest dates for each orange variety per year. Physicochemical properties (optical rotation, aldehyde content, ultraviolet [UV] absorbance, refractive index, and specific gravity) mandated by the United States Pharmacopeia (USP) for orange oil quality were assessed. Hamlin and Valencia oils showed minor differences in physicochemical properties based upon disease stage.

Prevalence and correlates of intimate partner violence victimization among men and women entering substance use disorder treatment.

Intimate partner violence victimization was examined in men (N = 4,459) and women (N = 1,774) entering substance use disorder treatment. Nearly 1 in 2 women and 1 in 10 men reported lifetime victimization by an intimate partner. Entering treatment for alcohol, as compared to drug abuse and history of childhood abuse, were each associated with intimate partner violence victimization.

Does a history of violence influence treatment, self-help, and 1-year outcomes in substance use disorder patients?

Rates of violence perpetration are high among patients with substance use disorder, but the impact of violence on substance use disorder treatment outcomes has received little attention. Patients with (n = 155) or without (n = 190) a history of difficulty controlling violent behavior were interviewed at entry to substance use disorder treatment and 1 year later. Substance use disorder severity, amount of treatment, and extent of participation in 12-step self-help groups were assessed to examine potential differences in treatment outcomes between violent and non-violent patients.

Impact of substance-use disorder treatment on women involved in prostitution: substance use, mental health, and prostitution one year after treatment.

Objective: Prostitution is common among women with substance-use disorders (SUDs). However, little is known about the outcomes of SUD treatment for women involved in prostitution relative to their peers or the impact of SUD treatment on subsequent prostitution.

Method: Participants were 1,287 women from a national study of SUD treatment sites.

Women's past-year prostitution status and receipt of substance abuse treatment services.

Objective: The study compared services received in substance abuse treatment programs by women who reported involvement in prostitution and by those who did not.

Methods: Women (N=1,604) in a national study of substance abuse programs completed a structured interview assessing substance abuse, demographic characteristics, and past-year prostitution at program entry. At discharge, information was gathered on treatment modality (residential including inpatient, or outpatient), duration, and amounts of medical, mental health, and psychosocial services received during treatment.

History of physical or sexual abuse and participation in 12-step self-help groups.

Objectives: Although 12-step groups are an important resource for managing substance use problems, their efficacy for patients with a physical or sexual abuse history is unknown.

Methods: In the present study, patients with a history of physical or sexual (n = 122) or no (n = 143) abuse were interviewed at entry to outpatient substance use treatment at the Veterans Administration.

Results: After adjusting for baseline substance use, physical or sexual abuse was associated with more attendance at and involvement in 12-step groups.

Child sexual abuse, early family risk, and childhood parentification: pathways to current psychosocial adjustment.

In this study, the authors examined the role of parentification (children assuming adult-like roles in the family) as it relates to family risk (parental psychopathology, parental illness, and domestic violence), child sexual abuse (CSA), and psychosocial adjustment in 499 college women. Structural equation modeling was used to test a model of direct, indirect, and mediational pathways through which CSA, family risk, and parentification contributed to later psychosocial maladjustment. Results indicate that CSA and family risk independently and directly predicted higher levels of maladjustment, but only family risk positively predicted parentification in childhood.

Lifetime physical and sexual abuse and substance use treatment outcomes in men.

Although lifetime physical and sexual abuse are common among substance use disorder (SUD) patients, few studies have examined the impact of abuse on treatment outcomes, particularly for men. Men with lifetime physical (n = 49), sexual (n = 49), or no abuse (n = 117) history were assessed at entry to outpatient SUD treatment and at 6 and 12 months postintake. Men with a history of physical or sexual abuse had more severe drug problems at intake, but by 6 months, there were no group differences in drug use.

Exposure to child abuse and risk for mental health problems in women.

Risk for adult mental health problems associated with child sexual, physical, or emotional abuse and multiple types of child abuse was examined. Logistic regression analyses were used to test study hypotheses in a population-based sample of women (N = 3,936). As expected, child sexual, physical, and emotional abuse were independently associated with increased risk for mental health problems.

Emotion socialization in maltreating and nonmaltreating mother-child dyads: implications for children's adjustment.

This study investigated maternal emotion socialization in physically maltreating and nonmaltreating mother-child dyads (N = 63 dyads) to examine the relation between maternal support in response to children's emotional displays and children's psychological adjustment (i.e., internalizing and externalizing behavior problems).

Synthesis of N2 2'-deoxyguanosine adducts formed by 1-nitropyrene.

[reaction: see text] Synthesis of N(2) 2'-deoxyguanosine adducts formed by the ubiquitous carcinogen, 1-nitropyrene, is reported. Various conditions of Buchwald-Hartwig palladium-catalyzed amination are examined. The most convenient synthetic approach involved a straightforward coupling between protected 2'-deoxyguanosine and bromonitropyrenes, which, upon reductive deprotection, provided excellent yield of the two 1-nitropyrene adducts.