Publications by authors named "Renee Merrell"
Background: The impact of antithrombotic agents (warfarin, clopidogrel, ASA) on traumatic brain injury outcomes is highly controversial. Although cerebral atrophy is speculated as a risk for acute intracranial hemorrhage, there is no objective literature evidence.
Materials And Methods: This is a retrospective, consecutive investigation of patients with signs of external head trauma and age ≥60 years.
In emergently ventilated trauma patients, low end-tidal CO2 and low cardiac output are associated and correlate with hemodynamic instability, hemorrhage, abnormal pupils, and death.
BMC Anesthesiol
September 2013
Article Synopsis
- The study reassessed the relationship between end-tidal carbon dioxide (PetCO2) and cardiac output (CO) in trauma patients requiring emergency intubation, following earlier findings that suggested a positive correlation between the two.
- Data was collected from 73 acutely injured trauma patients over several months, revealing significant connections between low PetCO2 and low CO, particularly in those with signs of serious injury such as hypotension and major blood loss.
- The research concluded that low levels of PetCO2 are linked to clinical indicators of hemodynamic instability and increased mortality, affirming the clinical relevance of monitoring both metrics during emergency resuscitation.
Background: Anoninvasive cardiac output (CO) monitor (NICOM), using Bioreactance technology, has been validated in several nontrauma patient studies. We hypothesized that NICOM CO would have more significant associations with clinical conditions than would systolic blood pressure (sBP).
Methods: This is a prospective observational study of consecutive trauma activation patients during the first 10 to 60 minutes after emergency department arrival.