A review and meta-analysis: Cross-tissue telomere length correlations in healthy humans.

Background And Aim: Tissue source has been shown to exert a significant effect on the magnitude of associations between telomere length and various health outcomes and exposures. The purpose of the present qualitative review and meta-analysis is to describe and investigate the impact of study design and methodological features on the correlation between telomere lengths measured in different tissues from the same healthy individual.

Methods: This meta-analysis included studies published from 1988 to 2022.

The interaction of socioeconomic stress and race on telomere length in children: A systematic review and meta-analysis.

Rationale: Proposed mechanisms relating early life exposures to poor health suggest that biologic indicators of risk are observable in childhood. Telomere length (TL) is a biomarker of aging, psychosocial stress, and a range of environmental exposures. In adults, exposure to early life adversity, including low socioeconomic status (SES), is predictive of shorter TL.

Method comparison studies of telomere length measurement using qPCR approaches: A critical appraisal of the literature.

Use of telomere length (TL) as a biomarker for various environmental exposures and diseases has increased in recent years. Various methods have been developed to measure telomere length. Polymerase chain reaction (PCR)-based methods remain wide-spread for population-based studies due to the high-throughput capability.